Introduction: Dental braces play an important role in restoring bite function, thus improving the physical and mental health and well-being of the individual. A modern and increasingly popular way of treating orthodontic anomalies is the invisible dental appliance. It is a transparent removable splint, which is changed by the wearer every one to three weeks and must be worn at least 22 hours daily. Its main advantage is that it is almost invisible in the mouth and is removable (Rošer, 2018). It allows easier and better oral hygiene and is more comfortable to wear than a conventional fixed appliance. Purpose: The aim is to investigate what changes invisible braces cause in the oral cavity. The thesis also provides a brief overview of the historical development, generations and range of materials currently used for the fabrication of invisible removable orthodontic splints. Methods: The work is based on a descriptive method of collecting, reviewing and analyzing peer-reviewed and scientific literature. The main sources are scientific articles and books in electronic format, accessible through online databases and browsers such as PubMed, ScienceDirect, Medline, Google scholar, Cinahl, Cochrane, COBISS. The literature search uses keywords and phrases in Slovene and English, such as orthodontic braces, orthodontic aligners, physical properties of orthodontic aligners, chemical properties of orthodontic aligners, impact of aligners on oral health. The practical part of this thesis includes the fabrication of an invisible removable orthodontic brace in a computer program. Results: The results show that the composition of the materials used in the manufacture of invisible removable orthodontic braces has an impact on their clinical performance. The importance of the chemical and physical properties of orthodontic splints is reflected in treatment efficacy and patient comfort. Discussion and conclusion: Research confirms that invisible removable orthodontic braces have undergone significant improvements since their first concepts, in particular through adaptations and innovations such as vacuum machining and CAD/CAM technology. The materials used for manufacturing must provide adequate chemical resistance, biocompatibility, mechanical strength and colour stability for long-term aesthetics and functionality. The accompanying advances in the manufacturing process using 3D scanning and digital modelling, together with precise placement of composite abutments, increase the accuracy and efficiency of orthodontic splint treatment.
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