Introduction: Teeth play one of the most important roles in a human's life, both in terms of function and beauty. The first materials that man used to replace teeth were natural materials, i.e. bones, teeth of animals and humans, ivory, etc. A new era for dental prosthetics began in the 19th century, after Goodyear invented the vulcanization process. Until the 18th century, the fiekd of dental prosthetics was considered very underdeveloped, however, it has gone through many stages of development in the field of dental materials, so today it belongs to one of the fastest developing fields. In the field of fixed prosthetics we know many types of materials these days that are used to make dental replacements. Dental alloys played an important role in the 20th century, as Co-Cr alloysappeared among the existing alloys. One of the most important and well-known materials in dental prosthetics is ceramics. The history of ceramics goes back as far as 3500 BC, but today it is consideres one of the most desirable materials, especially in the field of fixed prosthetics fort he production of dental substitutes, such as bridges, porcelain dental crowns, implants, etc. It is considered that all materials from which dental replacements are made must be biocompatible, because otherwise various problems can occur, such as various allergies, which can adversely affect the patient's health. Purpose: The purpose of this diploma work is to review the materials that were used in the field of fixed prosthetics in the past and the materials that are still used in this field today, and to present the importance of the biocompatibility of the materials from which tooth replacements are made. Methods: In the diploma work, we used a descriptive method of work with a systematic review of literature in Slovenian and foreign languages. We used the online databases Google Scholar, PubMed, ScienceDirect, ResearchGate and the library to review the literature. The literature used is in the scope of the last 10 years, and some literature that is older. Results: For the diploma work, we made a four-unit metal-porcelain bridge using the classic and digital manufacturing method. The substructure of the metal-porcelain bridge was digitally modeled in the CAD program, while the res tof the product was manufactured using the classic manufacturing method. In the production of the metal-porcelain bridge we followed the techniques described in the theoretical part of the diploma work using the descriptive method. Discussion and conclusion: Dental materials play one of the most important roles in the production of dental prostheses. Materials placed in the patient's mouth must be durable and biocompatible. Throughout history, the properties and biocompatibility of materials have improved significantly. In the addition to the classic methods of manufacturing dental replacements, the digital production of these is becoming more and more popular today. In fixed prosthetic treatments, the production of metal-porcelain dental restorstions is still very common today, but as a production technique, the fact is that digital techniques are becoming an increasingly common and popular choice, either in planning or in the final production of the prosthetic product itself.
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