Recent advances in the nickel-catalyzed alkylation of C-H bonds

Požgan, Franc (author), Grošelj, Uroš (author), Svete, Jurij (author), Štefane, Bogdan (author), Al Mamari, Hamad (author)

Functionalization of C-H bonds has emerged as a powerful strategy for converting inert, nonfunctional C-H bonds into their reactive counterparts. A wide range of C-H bond functionalization reactions has become possible by the catalysis of metals, typically from the second row of transition metals. First-row transition metals can also catalyze C-H functionalization, and they have the merits of greater earth-abundance, lower cost and better environmental friendliness in comparison to their second-row counterparts. C-H bond alkylation is a particularly important C-H functionalization reaction due to its chemical significance and its applications in natural product synthesis. This review covers Ni-catalyzed C-H bond alkylation reactions using alkyl halides and olefins as alkyl sources.

• Language: English
• Keywords: nickel, C-H activation, catalysis, C-H bond functionalization, C-H bond alkylation, Ni-catalysis, chelation assistance, cyclometalation
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: 27 str.
• Numbering: Vol. 29, iss. 9, art. 1917
• PID: 20.500.12556/RUL-158451
• UDC: 547:66.095.253:546.74
• ISSN on article: 1420-3049
• DOI: 10.3390/molecules29091917
• COBISS.SI-ID: 198576899
• Publication date in RUL: 12.06.2024

Record is a part of a journal

• Title: Molecules
• Shortened title: Molecules
• Publisher: MDPI
• ISSN: 1420-3049
• COBISS.SI-ID: 18462981

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: nikelj, C-H aktivacija, kataliza

Projects

• Funder: ARRS - Slovenian Research Agency
• Project number: P1-0179
• Name: Napredna organska sinteza in kataliza