Enhanced hemocompatibility and cytocompatibility of stainless steel

Benčina, Metka (avtor), Rawat, Niharika (avtor), Paul, Domen (avtor), Kovač, Janez (avtor), Lakota, Katja (avtor), Žigon, Polona (avtor), Kralj-Iglič, Veronika (avtor), Iglič, Aleš (avtor), Junkar, Ita (avtor)

The present study introduces an advanced surface modification approach combining electrochemical anodization and non-thermal plasma treatment, tailored for biomedical applications on stainless steel grade 316L (SS316L) surfaces. Nanopores with various diameters (100−300 nm) were synthesized with electrochemical anodization, and samples were further modified with non-thermal oxygen plasma. The surface properties of SS316L surfaces were examined by scanning electron microscopy, atomic force microscopy, X-ray photoemission spectroscopy, and Water contact angle measurements. It has been shown that a combination of electrochemical anodization and plasma treatment significantly alters the surface properties of SS316L and affects its interactions with blood platelets and human coronary cells. Optimal performance is attained on the anodized specimen featuring pores within the 150−300 nm diameter range, subjected to subsequent oxygen plasma treatment; the absence of platelet adhesion was observed. At the same time, the sample demonstrated good endothelialization and a reduction in smooth muscle cell adhesion compared to the untreated SS316L and the sample with smaller pores (100−150 nm). This novel surface modification strategy has significant implications for improving biocompatibility and performance of SS316L in biomedical applications.

• Jezik: Angleški jezik
• Ključne besede: surface modifications, electrochemical anodization, non-thermal plasma treatment, altered surface properties, blood platelets, human coronary stents, anatomy, anodization, cells, plasma, surface interactions
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FE - Fakulteta za elektrotehniko; ZF - Zdravstvena fakulteta ; MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2024
• Št. strani: Str. 19566–19577
• Številčenje: Vol. 9, iss. 17
• PID: 20.500.12556/RUL-156097
• UDK: 577
• ISSN pri članku: 2470-1343
• DOI: 10.1021/acsomega.4c01191
• COBISS.SI-ID: 193934339
• Datum objave v RUL: 08.05.2024

Gradivo je del revije

• Naslov: ACS omega
• Skrajšan naslov: ACS omega
• Založnik: American Chemical Society
• ISSN: 2470-1343
• COBISS.SI-ID: 525873945

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.