Prognostic factors of cataract surgery in patients with uveitis

Jevnikar, Kristina (author), Počkar, Saša (author), Umek, Lan (author), Rothova, Aniki (author), Vidović Valentinčič, Nataša (author)

Purpose To evaluate the long-term visual outcomes of patients with uveitis undergoing cataract surgery and to identify possible factors influencing the visual prognosis and the development of postoperative complications. Methods Retrospective study of all patients with uveitis who underwent cataract surgery between January 2015 and February 2020 in our tertiary referral center. Results A total of 78 eyes from 78 patients were included in the study. The best-corrected visual acuity (BCVA) improved in 86% of patients, and a BCVA of 0.5 or better was achieved in 57 (73%) patients. A significant correlation was shown between the preoperative and postoperative BCVA (Spearman r = 0.521, p < 0.01). Final BCVA differed between diverse anatomical uveitis entities (p = 0.047), and anterior uveitis demonstrated the best outcomes. Chronic uveitis resulted in a worse final BCVA than acute recurrent uveitis (p = 0.001). The presence of CME any time before the surgery and intermediate uveitis were associated with worse visual prognosis, while systemic therapy for uveitis before surgery and iris manipulation during surgery were not related to visual outcomes. Postoperative development of cystoid macular edema (CME) was closely associated with preexisting CME (p < 0.001) and intermediate uveitis (p = 0.01). Conclusions Visual results of cataract surgery in patients with uveitis were beneficial, but limited visual outcomes were more frequently observed in patients with chronic uveitis and intermediate uveitis with a history of CME. In consequence, prevention, or adequate treatment of CME, especially in patients with intermediate uveitis, might result in better visual results of their cataract surgery.

• Language: English
• Keywords: cataract, complications, cystoid macular edema, outcome, uveitis, phacoemulsification
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FU - Faculty of Administration; MF - Faculty of Medicine
• Publication status: Published
• Publication version: Version of Record
• Year: 2023
• Number of pages: Str. 4605–4612
• Numbering: Vol. 43, iss. 12
• PID: 20.500.12556/RUL-153134
• UDC: 61
• ISSN on article: 1573-2630
• DOI: 10.1007/s10792-023-02860-6
• COBISS.SI-ID: 165809923
• Publication date in RUL: 19.12.2023

Record is a part of a journal

• Title: International ophthalmology
• Shortened title: Int. ophthalmol.
• Publisher: Springer Nature
• ISSN: 1573-2630
• COBISS.SI-ID: 513171481

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• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.