Graphene, an extraordinary two-dimensional material, has garnered significant attention due to its exceptional properties and potential applications across various fields. As the use of graphene continues to expand, concerns have arisen about its impact on the environment and sustainable development. One of the key features to consider is the biodegradability of different forms of graphene. Biodegradation occurs in nature as a natural process of breaking down materials in the presence of microorganisms, fungi, or other biological activities. Understanding how materials such as graphene degrade in a natural environment is crucial for assessing potential risks, exploring their long-term effects, and developing sustainable applications. In our work, we introduced the fundamental categorization, individual factors and detection methods of the biodegradation process of different forms of graphene. We focused on the question of biodegradability, where we examined several existing studies related to graphene family members. We assessed the biological degradability of graphene, including graphene oxide, reduced graphene oxide, phosphate graphene and graphene quantum dots. We shed light on importance of biodegradability for applications of graphene across various fields. Results of various studies led us to final conclusion that these materials are able to degrade through the process of biodegradation. The main factors that influence biodegradability of graphene materials and the process of biodegradation are their structural characteristics and specific conditions in which they are immersed.
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