Izvedba difuzijsko-perfuzijskega slikanja pri MR preiskavi prostate : diplomsko delo

Jurjec, Vesna (author), Omerzu, Vesna (author), Podobnik, Janez (mentor), Breznik, Andrej (co-mentor), Žager Marciuš, Valerija (reviewer)

Uvod: Prostata ali obsečnica je žleza v velikosti oreha, ki se nahaja med mehurjem in moškim spolnim udom. Najpogostejša patološka stanja so prostatitis, benigna hiperplazija prostate in rak prostate. Za diagnosticiranje teh patoloških stanj se uporablja multiparametrično slikanje prostate z magnetno resonanco. To je posebna preiskava, ki ustvari podrobnejše slike prostate v primerjavi s klasično magnetno resonančno preiskavo. Je morfološko, difuzijsko in perfuzijsko slikanje. Pod morfološko slikanje spadajo T1 in T2 poudarjene slike. Uporaba difuzijskih in perfuzijskih slik nam omogoča natančno lokalizacijo patološkega tkiva in pridobitev funkcionalnega stanja male medenice Namen: Namen diplomskega dela je predstaviti smernice Evropskega združenja za urogenitalno radiologijo za izvedbo difuzijsko-perfuzijskega slikanja prostate z magnetno resonanco ter evalvacija tehnične izvedbe protokola v Splošni bolnišnici Celje v primerjavi z mednarodnimi priporočili in smernicami. Metode dela: Izvedli smo retrospektivno študijo opravljenih kliničnih preiskav. Pacienti vključeni v preiskavo so imeli opravljeno magnetno resonanco male medenice s kontrastnim sredstvom. Ležali so na hrbtu z glavo proti magnetnoresonančni odprtini aparata. Rezultati: Predstavili smo slike uporabljenih pulznih zaporedij ter tehnične parametre le-teh. Razprava in zaključek: Večparametrično slikanje z magnetno resonanco je posebna preiskava, ki predstavi podrobnejše slike prostate kot klasično magnetnoresonančno slikanje. Pri tej preiskavi se poleg T1 in T2 poudarjenih slik uporabi difuzijsko in perfuzijsko slikanje. S temi pulznimi zaporedji lahko ocenimo morfološke značilnosti prostate, natančno lokalizacijo patološkega tkiva ter funkcionalno stanje male medenice. Po izvedbi evalvacije tehničnih parametrov uporabljenih v Splošni bolnišnici Celje z mednarodnimi smernicami smo ugotovili, da so parametri Splošne bolnišnice Celje v večini primerih optimalni in nekaterih primerih delno optimalni z mednarodnimi priporočili in smernicami.

• Language: Slovenian
• Keywords: diplomska dela, radiološka tehnologija, prostata, večparametrično slikanje z magnetno resonanco, difuzija, perfuzija
• Work type: Bachelor thesis/paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: ZF - Faculty of Health Sciences
• Place of publishing: Ljubljana
• Publisher: [V. Jurjec : V. Omerzu]
• Year: 2023
• Number of pages: 36 str., [2] str. pril.
• PID: 20.500.12556/RUL-149618
• UDC: 616-07
• COBISS.SI-ID: 163737859
• Publication date in RUL: 08.09.2023

Secondary language

• Language: English
• Title: Performance of diffusion-perfusion imaging in MR of the prostate : diploma work

Abstract

Introduction: The prostate is a walnut-sized gland located between the urinary bladder and the male sex organ. The most common pathological conditions are prostatitis, benign prostatic hyperplasia and prostate cancer. Multiparametric magnetic resonance imaging of the prostate is used to diagnose these conditions. This is a special examination that provides more detailed images of the prostate compared to conventional magnetic resonance imaging. It involves morphological, diffusion and perfusion imaging. Morphologic imaging includes T1-weighted and T2-weighted images. The use of diffusion and perfusion imaging allows for accurate localisation of pathologic tissue and determination of pelvic functional status. Purpose: The aim of the thesis is to present the guidelines of the European Association of Urogenital Radiology for the performance of diffusion-perfusion magnetic resonance imaging of the prostate and to evaluate the technical implementation of the protocol at Splošna bolnišnica Celje in comparison with international recommendations and guidelines. Methods: We performed a retrospective study of the clinical examinations performed. Patients included in the study underwent magnetic resonance imaging of the small pelvis with contrast medium. They lay in the supine position with their heads facing the opening of the magnetic resonance imaging machine. Results: We presented images of the sequences used and their technical parameters. Discussion and conclusion: Multiparametric magnetic resonance imaging is a special examination that provides more detailed images of the prostate than conventional magnetic resonance imaging. In addition to T1 and T2-weighted images, diffusion and perfusion images are also used in this examination. These sequences can be used to assess the morphologic features of the prostate, the precise location of pathologic tissue, and the functional status of the pelvis. After evaluating the technical parameters used in Splošna bolnišnica Celje with the international guidelines, we found out that the parameters used in Splošna bolnišnica Celje are in most cases optimal and in few cases partially optimal with the international recommendations and guidelines.

• Keywords: diploma theses, radiological technology, prostate, multiparametric magnetic resonance imaging, diffusion, perfusion