Introduction: Humans are increasingly exposed to persistent and dangerous chemicals, whose negative effects on human and animal health, as well as on the environment, are only now beginning to be understood. Because of their ability to bioaccumulate, they accumulate in humans and in the ecosystem. Because they are soluble in water, they can be distributed throughout the entire water system. For these reasons, rapid and efficient methods for detection of these chemicals is required. Analytical methods, of which there are several types, are currently the most widely used for the detection of these chemicals, but due to their persistence in the environment, these methods are difficult to implement. Persistent and dangerous chemicals are analytically determined most easily by using chromatography, which also includes the high pressure liquid chromatography. Depending on the type of analyte, during the analysis we may encounter various and even many parameters that can complicate the process. Various technologies have been developed for the electrochemical determination of these chemicals, classified according to chemical recognition agents. In recent years, electrochemical sensors have attracted a lot of attention, which, in contrast to analytical methods, are low-cost, fast, simple, easy, and also highly sensitive and small. Purpose: The aim is to examine the sensitivity of the analytical method for determining persistent and dangerous chemicals for the compounds melamine, bezotriazole, bisphenol s and benzisothiazolinone. And check the sensitivity of the sensors for detecting bisphenol S. Methods: A comparison of the analytical method using a high-resolution liquid chromatograph and three different types of electrodes for thedetermination of low concentrations of bisphenol S was carried out, as well as the performance of calibration curves for melamine, benzoriazole and benzisothiazolinone. Results: With the help of a high-resolution liquid chromatograph, we detected concentrations of up to 0.001 μM for benzotriazole and even lower concentrations for the other compounds. With the help of sensors, concentrations of bisphenol S were only as low as 1 μM. Which means that with the help of analytical methods we can detect lower concentrations than with the help of electrochemical methods. Discussion and conclusion: With the help of analytical methods, lower concentrations can be detected than with the help of electrochemical methods, which means that the methods would have to be modified in order to make sensors, since low concentrations of these compounds are found in the environment. For use in sensors, commercial screen printed electrodes would be the most suitable, since with these electrodes the results vary the least, but optimization of the methods would still be necessary.
|
