Robustness of diffuse reflectance spectra analysis by inverse adding doubling algorithm

Tomanič, Tadej (avtor), Rogelj, Luka (avtor), Milanič, Matija (avtor)

Analysing diffuse reflectance spectra to extract properties of biological tissue requires modelling of light transport within the tissue, considering its absorption, scattering, and geometrical properties. Due to the layered skin structure, skin tissue models are often divided into multiple layers with their associated optical properties. Typically, in the analysis, some model parameters defining these properties are fixed to values reported in the literature to speed up the fitting process and improve its performance. In the absence of consensus, various studies use different approaches in fixing the model parameters. This study aims to assess the effect of fixing various model parameters in the skin spectra fitting process on the accuracy and robustness of a GPU-accelerated two-layer inverse adding-doubling (IAD) algorithm. Specifically, the performance of the IAD method is determined for noiseless simulated skin spectra, simulated spectra with different levels of noise applied, and in-vivo measured reflectance spectra from hyperspectral images of human hands recorded before, during, and after the arterial occlusion. Our results suggest that fixing multiple parameters to a priori known values generally improves the robustness and accuracy of the IAD algorithm for simulated spectra. However, for in-vivo measured spectra, these values are unknown in advance and fixing optical parameters to incorrect values significantly deteriorates the overall performance. Therefore, we propose a method to improve the fitting performance by pre-estimating model parameters. Our findings could be considered in all future research involving the analysis of diffuse reflectance spectra to extract optical properties of skin tissue.

• Jezik: Angleški jezik
• Ključne besede: medical physics, biomedical optics
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: FMF - Fakulteta za matematiko in fiziko
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2022
• Št. strani: Str. 921-949
• Številčenje: Vol. 13, no. 2, art. 443880
• PID: 20.500.12556/RUL-145312
• UDK: 616-073:535
• ISSN pri članku: 2156-7085
• DOI: 10.1364/BOE.443880
• COBISS.SI-ID: 94642435

Avtorske pravice

“© 2022 Optica Publishing Group under the terms of the Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for noncommercial purposes and appropriate attribution is maintained. All other rights are reserved.” (Datum opombe: 17. 4. 2023)

• Datum objave v RUL: 17.04.2023

Gradivo je del revije

• Naslov: Biomedical optics express
• Skrajšan naslov: Biomed. opt. express
• Založnik: Optica
• ISSN: 2156-7085
• COBISS.SI-ID: 24857383

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: medicinska fizika, biomedicinska optika

Projekti

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: J3-3083
• Naslov: Vaskularizacija in vaskularni učinki kot prognostični dejavniki za zdravljenje tumorjev z lokalnimi ablacijskimi tehnikami

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: P1-0389
• Naslov: Medicinska fizika