Prognostic impact of nonobstructive coronary artery disease detected by coronary computed tomographic angiography

Košuta, Daniel (avtor), Jug, Borut (avtor), Fras, Zlatko (avtor)

Coronary computed tomographic angiography (CCTA) is a promising technique for ruling out coronary artery disease (CAD) in patients with chest pain. We aimed to investigate the prognostic impact of nonobstructive CAD on CCTA. We retrospectively reviewed patients who underwent CCTA between 2010 and 2016 at our institution. We divided them into 3 groups: (1) patients with no CAD, (2) patients with nonobstructive CAD, and (3) patients with obstructive CAD. We investigated the incidence of the primary outcome (combination of death, nonfatal myocardial infarction, unstable angina, and late revascularization). A total of 989 patients were included: 540 patients had CAD, which was obstructive (≥50% stenosis) in 256 cases. During the follow-up period, 99 events occurred (32 [7%] in patients without CAD, 26 [9%] in patients with nonobstructive CAD, and 41 [16%] in patients with obstructive CAD; P < .001). The presence of nonobstructive and obstructive CAD was an independent predictor of events (HR: 2.33 [1.15-4.69], P < .001; and 4.02 [1.98-8.13], P = .019, respectively) compared with no CAD. Nonobstructive CAD on CCTA is associated with a 2-fold increase in risk of coronary events compared with patients with no CAD.

• Jezik: Angleški jezik
• Ključne besede: coronary artery disease, coronary computed tomographic angiography, prognosis
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: Str. 749-753
• Številčenje: Vol. 72, iss. 8
• PID: 20.500.12556/RUL-144110
• UDK: 616.1
• ISSN pri članku: 0003-3197
• DOI: 10.1177/0003319721999494
• COBISS.SI-ID: 56835075
• Datum objave v RUL: 01.02.2023

Gradivo je del revije

• Naslov: Angiology
• Skrajšan naslov: Angiology
• Založnik: SAGE
• ISSN: 0003-3197
• COBISS.SI-ID: 247063

Licence

• Licenca: CC BY-NC 4.0, Creative Commons Priznanje avtorstva-Nekomercialno 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc/4.0/deed.sl
• Opis: Licenca Creative Commons, ki prepoveduje komercialno uporabo, vendar uporabniki ne rabijo upravljati materialnih avtorskih pravic na izpeljanih delih z enako licenco.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: koronarna arterijska bolezen, koronarna računalniška tomografija, angiografija, prognoza