A pathophysiological intersection of diabetes and Alzheimer’s disease

Čater, Maša (author), Hölter, Sabine M. (author)

Diabetes is among the most prevalent diseases of the modern world and is strongly linked to an increased risk of numerous neurodegenerative disorders, although the exact pathophysiological mechanisms are not clear yet. Insulin resistance is a serious pathological condition, connecting type 2 diabetes, metabolic syndrome, and obesity. Recently, insulin resistance has been proven to be connected also to cognitive decline and dementias, including the most prevalent form, Alzheimer’s disease. The relationship between diabetes and Alzheimer’s disease regarding pathophysiology is so significant that it has been proposed that some presentations of the condition could be termed type 3 diabetes.

• Language: English
• Keywords: diabetes, insulin sensitivity, Alzheimer’s disease, brain, cognition, depression
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: BF - Biotechnical Faculty
• Year: 2022
• Number of pages: 21 str.
• Numbering: Vol. 23, iss. 19, art. 11562
• PID: 20.500.12556/RUL-141923
• UDC: 616
• ISSN on article: 1422-0067
• DOI: 10.3390/ijms231911562
• COBISS.SI-ID: 123846915
• Publication date in RUL: 11.10.2022

Record is a part of a journal

• Title: International journal of molecular sciences
• Shortened title: Int. j. mol. sci.
• Publisher: MDPI
• ISSN: 1422-0067
• COBISS.SI-ID: 2779162

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: medicina, diabetes, Alzheimerjeva bolezen, patofiziologija