The aim of this study was to collect and analyze data from an experiment in which we fed isocaloric diets to a lean line (FHI) and a fat line (FLI) of mice, but with different compositions-a high fat diet (HFD) and a low fat diet (LFD). We were interested in whether these two types of diets had an effect on the difference in growth of the mice and fat deposition depending on the genotype FHI or FLI. Obesity is associated with insulin resistance. Research shows that adipose tissue plays an important role in the development and progression of diseases related to obesity. High fat intake leads to changes in adipose tissue metabolism, increasing the level of free fatty acids in the blood, which has a negative effect on metabolism. We used 42 mice of the FHI and FLI lines (24 FHI, 18 FLI) for the procedure. The mice were enrolled in the study at 21-25 days of age. They were divided into two groups for each line. One group was fed low-fat diet and the other high fat diet. The results showed that the effect of genotype was not significant in the low-fat treatment. In the group fed high fat diet, we found statistically significant differences in the measured traits between FLI and FHI genotypes.
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