Recently, there has been a growing awareness that the fight to preserve a human-friendly environment must take place at all levels. Correspondingly, interest and new ways of reacting under green conditions are also increasing. Aromatic ketones are components of many different substances. They are present in pharmaceutical products, natural products and agrochemicals.
The thesis presents Friedel-Crafts acylation of polysubstituted and activated aromatic compounds with one or two rings. Substituents are methoxy and methyl groups. With one exception, the reactions were carried out without a metal catalyst and with significantly less produced waste than in classic synthesis. One reaction was performed under traditional conditions with acetyl chloride and AlCl3 due to the failure of the reaction under green conditions. Some of the resulting products have not yet been described in the currently available literature.
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