Optimizacija sinteze izbranih derivatov piritiona in priprava njihovih cinkovih koordinacijskih spojin

Poljanc, Benjamin (author), Turel, Iztok (mentor)

Cilj diplomske naloge je bila optimizacija že znane sintezne poti za pripravo piritionov s trifluorometilno skupino in uporaba le-teh za sintezo cinkovih koordinacijskih spojin. Pri eksperimentalnem delu so bili sintetizirani štirje analogi piritiona s trifluorometilno skupin na različnih položajih aromatskega obroča, ki so bili nato uporabljeni kot ligandi za sintezo cinkovih koordinacijskih spojin. Sintetizirani piritioni in njihovi cinkovi kompleksi so bili karakterizirani z jedrsko magnetno resonanco (NMR) ter z UV-Vis in IR spektroskopijo. Pripravljeni piritioni so bili dodatno karakterizirani tudi z masno spektrometrijo.

• Language: Slovenian
• Keywords: optimizacija, substituirani piritioni, fluor, cink
• Work type: Bachelor thesis/paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Year: 2022
• PID: 20.500.12556/RUL-139702
• COBISS.SI-ID: 126254595
• Publication date in RUL: 06.09.2022

Secondary language

• Language: English
• Title: Optimisation of synthesis of selected pyrithione derivatives and preparation of their coordination compounds with zinc

Abstract

The aim of my work was to optimize an already known synthetic route of pyrithiones with trifluoromethyl group and to prepare their coordination compounds with zinc. Four different pyrithione analogues with different positions of the trifluoromethyl group on the aromatic ring were synthesized and later used as ligands for the preparation of zinc complexes. The synthesized pyrithiones and their zinc complexes were characterized by nuclear magnetic resonance (NMR), UV-Vis and IR spectroscopy. The pyrithiones were also characterized by mass spectrometry.

• Keywords: optimisation, substituted pyrithiones, fluorine, zinc