Induced pluripotent stem cell (iPSC) line MLi004-A derived from a patient with recessive dystrophic epidermolysis bullosa (RDEB)

Ropret, Sandra (avtor), Jeriha, Jakob (avtor), Sorčan, Tjaša (avtor), Rogar, Marija (avtor), Zemljič Jokhadar, Špela (avtor), McGrath, John A. (avtor), Ilic, Dusko (avtor), Liović, Mirjana (avtor)

We have generated MLi004-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a female patient with recessive dystrophic epidermolysis bullosa (RDEB). This iPSC line may be used as a model system for studies on skin integrity, the extracellular matrix and skin barrier function. The characterization of the MLi004-A cell line consisted of molecular karyotyping, next-generation sequencing of the COL7A1 alleles, plu-ripotency and differentiation potentials testing by immunofluorescence of associated markers in vitro. The MLi004-A line has been also tested for ability to differentiate into fibroblasts.

• Jezik: Angleški jezik
• Ključne besede: stem cell, epidermolysis, collagen VII, recessive dystrophic EB, iPSC line, pluripotency, fibroblast, keratinocyte
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 5 str.
• Številčenje: Vol. 55, art. 102463
• PID: 20.500.12556/RUL-138881
• UDK: 61
• ISSN pri članku: 1876-7753
• DOI: 10.1016/j.scr.2021.102463
• COBISS.SI-ID: 74980611
• Datum objave v RUL: 24.08.2022

Gradivo je del revije

• Naslov: Stem cell research
• Založnik: Elsevier
• ISSN: 1876-7753
• COBISS.SI-ID: 524165401

Licence

• Licenca: CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
• Opis: Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: matične celice, epidermoliza, kolagen VII