Vrednotenje in primerjava sprememb Pharmaceutical Care Network Europe klasifikacije težav, povezanih z zdravili

Gladek, Mojca (author), Horvat, Nejc (mentor)

Odkrivanje, preprečevanje, reševanje in spremljanje težav, povezanih z zdravili, predstavlja enega izmed temeljev izvajanja farmacevtske skrbi. Najpogosteje se jih določa s pomočjo ene izmed klasifikacij težav, povezanih z zdravili. Te se med seboj razlikujejo v obliki, vsebini ter namenu in načinu uporabe. Med pogosteje uporabljenimi klasifikacijami je Pharmaceutical Care Network Europe (PCNE) klasifikacija težav, povezanih z zdravili, ki pa jo raziskovalci med svojim raziskovalnim delom pogosto spreminjajo. Namen magistrske naloge je bil vrednotiti in primerjati spremembe PCNE klasifikacije težav, povezanih z zdravili, ki jih raziskovalci izvedejo v procesu določanja težav, povezanih z zdravili. Na začetku smo izvedli pregled literature in tako poiskali članke, katerih avtorji so v sklopu svojega dela spremenili eno izmed uradnih verzij PCNE klasifikacije. Vsem tem avtorjem smo v izpolnjevanje poslali spletni anketni vprašalnik, s pomočjo katerega smo želeli pridobiti podrobnejše podatke o naravi in vzrokih sprememb ter uradni verziji klasifikacije, ki so jo spremenili. Pri raziskovalcih, ki niso izpolnili spletnega anketnega vprašalnika, smo podatke poskušali preveriti pozneje. Iz objavljenih člankov smo pridobili vse podatke o spremembah PCNE klasifikacije težav, povezanih z zdravili, in jim seznam poslali v potrditev. Devet od 18 raziskovalcev (50 %) je izpolnilo spletni anketni vprašalnik oz. podatke potrdilo v poznejšem preverjanju podatkov. Za preostalih devet raziskav smo predpostavili pravilnost podatkov, ki smo jih sami pridobili iz objavljenih člankov. Skupaj je 12 raziskovalcev (66,7 %) med svojim delom spremenilo PCNE klasifikacijo V5.01 ali V6.2, šest raziskovalcev (33,3 %) pa je oblikovalo lastno klasifikacijo, ki je temeljila na več različnih klasifikacijah, ena izmed njih je bila tudi PCNE klasifikacija. Devet spremenjenih klasifikacij (50 %) je mogoče primerjati z uradno verzijo PCNE klasifikacije vsaj v enem izmed poglavij, štiri spremenjene klasifikacije (22,2 %) pa so primerljive v celoti. Petih spremenjenih klasifikacij (27,8 %) ni mogoče primerjati z uradnimi verzijami PCNE klasifikacije. To velja predvsem za tiste klasifikacije, ki so jih razvili na podlagi različnih (ne samo PCNE) klasifikacij. V prihodnje verzije PCNE klasifikacije je v sklopu že obstoječih domen smiselno vpeljati še 13 dodatnih poddomen in dve povsem novi domeni s skupno 13 poddomenami. Na novo vpeljane poddomene bi zajemale predvsem tehnične težave, povezane z zdravili.

• Language: Slovenian
• Keywords: težave, povezane z zdravili, klasifikacija težav, povezanih z zdravili, PCNE, spremembe, primerljivost
• Work type: Master's thesis/paper
• Organization: FFA - Faculty of Pharmacy
• Year: 2022
• PID: 20.500.12556/RUL-137041
• Publication date in RUL: 31.05.2022

Secondary language

• Language: English
• Title: Evaluation and comparison of modifications of the Pharmaceutical Care Network Europe drug-related problems classification

Abstract

The detection, prevention, resolution and monitoring of drug-related problems is one of the cornerstones of pharmaceutical care. Drug-related problems are usually classified using one of the many classifications linked to assessing drug-related challenges in the pharmaceutical care. We can distinguish them based on their form, content, purpose and method of use. One of the most commonly used classifications is the Pharmaceutical Care Network Europe (PCNE) classification, which has been modified by many researchers around the world. The aim of this Master's thesis was to evaluate and compare the modifications of the PCNE classification of drug-related problems. We started the study with a systematic review of the published literature and continue to search for articles whose authors stated that they had modified one of the official versions of the PCNE classification for the needs of their own research. The next taken step was to send an online questionnaire to these authors to obtain more detailed information about which official version of the classification they had modified, what modifications they had made and why they had made them. All researchers who did not complete the online questionnaire were sent an email with information on modifications they had made to the classification and were asked to confirm them. Nine out of 18 researchers (50 %) completed the online questionnaire or confirmed the information provided in the email. For the remaining nine researchers, we assumed the accuracy of the information about modifications made to the PCNE classification that we had obtained ourselves from published articles. Twelve researchers (66.7 %) modified either the PCNE classification V5.01 or the PCNE classification V6.2 and six researchers (33.3 %) developed their own classification based on several different classifications, one of which was also the PCNE classification. Nine modified classifications (50 %) can be compared with the official version of the PCNE classification based on at least one of the sections, and four modified classifications (22.2 %) are fully comparable. Five modified classifications (27.8 %), mostly those developed on the basis of other classifications, cannot be compared with the official versions of the PCNE classification. For future versions of the PCNE classification of drug-related problems, we propose 13 new subdomains and two new domains with a total of 13 subdomains, which would mainly allow for the classification of technical drug-related problems.

• Keywords: drug-related problems, classification of drug-related problems, PCNE, modifications, comparison