Diagnostic and therapeutic values of angiogenic factors in endometrial cancer

Roškar, Luka (avtor), Roškar, Irena (avtor), Lanišnik-Rižner, Tea (avtor), Smrkolj, Špela (avtor)

Endometrial cancer (EC) is the most frequent gynecological malignancy in developed countries and requires a relatively invasive diagnostic evaluation and operative therapy as the primary therapeutic approach. Angiogenesis is one of the main processes needed for cancer growth and spread. The production of angiogenic factors (AFs) appears early in the process of carcinogenesis. The detection of AFs in plasma and tissue and a better understanding of the angiogenic properties of EC may contribute not only to earlier but also more specific diagnosis and consequently tailored and individual therapeutic approaches. AFs and their receptors also have high potential as binding sites for targeted cancer therapy. In this review, we discuss angiogenesis in EC and the characteristics of the AFs that most contribute to angiogenesis in EC. We also highlight therapeutic strategies that target angiogenesis as potential EC therapy.

• Jezik: Angleški jezik
• Ključne besede: endometrial cancer, angiogenesis, biomarkers, angiogenic factors, anti-angiogenic therapy
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2022
• Št. strani: 14 str.
• Številčenje: Vol. 12, iss. 1, art. 7
• PID: 20.500.12556/RUL-136913
• UDK: 616-006
• ISSN pri članku: 2218-273X
• DOI: 10.3390/biom12010007
• COBISS.SI-ID: 90507523
• Datum objave v RUL: 24.05.2022

Gradivo je del revije

• Naslov: Biomolecules
• Skrajšan naslov: Biomolecules
• Založnik: MDPI
• ISSN: 2218-273X
• COBISS.SI-ID: 519952921

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.01.2022

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: rak endometrija, angiogeneza, biomarkerji