Toxoplasma gondii is a parasite that causes toxoplasmosis. Immunocompetent people who become infected often do not have symptoms, however people with compromised immune systems may experience more severe symptoms. Pregnant women that become infected fort he first time during pregnancy present special problem, because it may result in miscarriage or congenital infection of fetus. In Slovenia there is a national serological screening programme of pregnant women since 1995. The purpose of this programme is detection of infection in pregnant women early enough so the transmission to the fetus can be prevented. With our master thesis we wanted to determine the seroprevalnce of toxoplasmosis amongst pregnant women in Slovenia from 2008 until 2019. We collected the data from the database of Institute of microbiology and immunology. Pregnant women were tested for the IgG and IgM anti-Toxoplasma gondii antibodies. In some cases avidity of IgG antibodies was also tested. In our study we covered 61.598 pregnancies. For statistical analysis we used R programme version 4.0.2. We observed that seroprevalence dropped from 0,316 (95 % CI: 0,290-0,342) to 0,168 (95 % CI: 0,148-0,187). Intergravid incidence in this preriod was 0,54 %. In relation to previous studies done in Slovenia we observed the decline of accute infections in pregnant women. Intragravid incidence was 0,43 %. We did not notice statistically distinguishable difference between intra- and intergravid incidence. Our study suggests that serological screening programme of pregnant women in Slovenia is effective.
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