Risk assessment of oxidative stress induced by metal ions released from fixed orthodontic appliances during treatment and indications for supportive antioxidant therapy : a narrative review

Primožič, Jasmina (avtor), Poljšak, Borut (avtor), Jamnik, Polona (avtor), Kovač, Vito (avtor), Čanadi-Jurešić, Gordana (avtor), Špalj, Stjepan (avtor)

The treatment with fixed orthodontic appliances could have an important role in the induction of oxidative stress and associated negative consequences. Because of the simultaneous effects of corrosion, deformation, friction, and mechanical stress on fixed orthodontic appliances during treatment, degradation of orthodontic brackets and archwires occurs, causing higher concentrations of metal ions in the oral cavity. Corroded appliances cause the release of metal ions, which may lead to the increased values of reactive oxygen species (ROS) due to metal-catalyzed free radical reactions. Chromium, iron, nickel, cobalt, titanium, and molybdenum all belong to the group of transition metals that can be subjected to redox reactions to form ROS. The estimation of health risk due to the amount of heavy metals released and the level of selected parameters of oxidative stress generated for the time of treatment with fixed orthodontic appliances is presented. Approaches to avoid oxidative stress and recommendations for the preventive use of topical or systemic antioxidants during orthodontic treatment are discussed.

• Jezik: Angleški jezik
• Ključne besede: fixed orthodontic appliances, oxidative stress, metal ions, risk assessment, antioxidant therapy
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.02 - Pregledni znanstveni članek
• Organizacija: MF - Medicinska fakulteta ; ZF - Zdravstvena fakulteta ; BF - Biotehniška fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 17 str.
• Številčenje: Vol. 10, iss. 9, art. 1359
• PID: 20.500.12556/RUL-136042
• UDK: 616.314-089.23:546.7:66.094.3.097.8
• ISSN pri članku: 2076-3921
• DOI: 10.3390/antiox10091359
• COBISS.SI-ID: 74268163
• Datum objave v RUL: 08.04.2022

Gradivo je del revije

• Naslov: Antioxidants
• Skrajšan naslov: Antioxidants
• Založnik: MDPI
• ISSN: 2076-3921
• COBISS.SI-ID: 522976025

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.09.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: ortodontski pripomočki, oksidativni stres, kovinski ioni, vpliv na zdravje, antioksidanti