Prevalence and risk factors for lymphocytic choriomeningitis virus infection in continental Croatian regions

Vilibić-Čavlek, Tatjana (avtor), Oreški, Tena (avtor), Korva, Miša (avtor), Kolarič, Branko (avtor), Stevanovic, Vladimir (avtor), Židovec-Lepej, Snježana (avtor), Tabain, Irena (avtor), Jelicic, Pavle (avtor), Miklausic-Pavic, Bozana (avtor), Savić, Vladimir (avtor), Barbić, Ljubo (avtor), Avšič-Županc, Tatjana (avtor)

Lymphocytic choriomeningitis virus (LCMV) is a neglected human pathogen associated with aseptic meningitis, severe systemic infections in immunocompromised persons, and congenital anomalies. Data on the prevalence of LCMV infections are scarce. We analyzed the seroprevalence of LCMV in continental Croatian regions. A total of 338 serum samples of professionally exposed (forestry workers, hunters, agriculture workers in contact with rodents) and non-exposed populations (general population, pregnant women) were tested for the presence of LCMV antibodies using indirect immunofluorescence assay. No participants reported recent febrile disease. LCMV IgG antibodies were detected in 23/6.8% of participants: 9.8% exposed persons and 5.1% non-exposed persons (6.1% in the general population and 3.9% in pregnant women). No participants were LCMV IgM positive. Although higher seropositivity was found in males compared to females (8.9% vs. 4.7%), inhabitants of suburban/rural areas compared to inhabitants of urban areas (9.2% vs. 4.6%), and persons who used well as a source of water compared to those who used tap (11.4% vs. 5.6%), these differences did not reach statistical significance. Results of logistic regression showed that the presence of rodents in the house/yard and cleaning rodent nests were associated with an elevated risk for LCMV infection (OR = 2.962, 95% CI = 1.019–8.607).

• Jezik: Angleški jezik
• Ključne besede: lymphocytic choriomeningitis virus, seroprevalence, general population, professionally exposed, pregnant women, Croatia
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 10 str.
• Številčenje: Vol. 6, iss. 2, art. 67
• PID: 20.500.12556/RUL-135509
• UDK: 616.9
• ISSN pri članku: 2414-6366
• DOI: 10.3390/tropicalmed6020067
• COBISS.SI-ID: 67793923
• Datum objave v RUL: 17.03.2022

Gradivo je del revije

• Naslov: Tropical medicine and infectious disease
• Skrajšan naslov: Trop. med. infect. dis.
• Založnik: MDPI
• ISSN: 2414-6366
• COBISS.SI-ID: 526463769

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.06.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: virus limfocitnega horiomeningitisa, seroprevalenca, splošno prebivalstvo

Projekti

• Financer: Drugi - Drug financer ali več financerjev
• Program financ.: University of Zagreb, School of Medicine
• Naslov: Prevalence of lymphocytic choriomeningitis in the Croatian mainland

• Financer: EC - European Commission
• Program financ.: H2020
• Številka projekta: 653316
• Naslov: European Virus Archive goes global
• Akronim: EVAg