Microwave-assisted multicomponent syntheses of heterocyclic phosphonates

Bálint, Erika (avtor), Popovics-Tóth, Nóra (avtor), Tajti, Ádám (avtor), Rávai, Bettina (avtor), Szabó, Kármen Emőke (avtor), Perdih, Franc (avtor)

Organophosphorus compounds play an important role in the medicinal- or agricultural industry, and in the human body as well. Over the last years, heterocyclic phosphonates have received growing interest due to their potential biological activity. An efficient tool for the preparation of such derivatives is their synthesis via multicomponent reactions. These transformations possess several criteria of an “ideal synthesis”, such as high atom economy, fast and simple accomplishment, energy efficiency, and environmentally friendliness. A number of heterocyclic phosphonates were prepared by us utilizing multicomponent syntheses. In this proceeding, the synthesis of the diethyl (2-amino-3-cyano-4H-chromen-4-yl)phosphonate by the condensation of salicylaldehyde, malononitrile and diethyl phosphite is briefly introduced. The reaction was optimized in respect of the catalyst type, the catalyst amount, the reaction time, and the temperature.

• Jezik: Angleški jezik
• Ključne besede: microwave, three-component reaction, multicomponent synthesis, (4H-chromen-4-yl)phosphonate
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.08 - Objavljeni znanstveni prispevek na konferenci
• Organizacija: FKKT - Fakulteta za kemijo in kemijsko tehnologijo
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2021
• Št. strani: 5 str.
• Številčenje: Vol. 3, iss. 1, art. 108
• PID: 20.500.12556/RUL-135321
• UDK: 547.7/.8
• ISSN pri članku: 2673-4583
• DOI: 10.3390/ecsoc-24-08548
• COBISS.SI-ID: 64358915
• Datum objave v RUL: 08.03.2022

Gradivo je del revije

• Naslov: Chemistry proceedings
• Skrajšan naslov: Chem. proc.
• Založnik: MDPI
• ISSN: 2673-4583
• COBISS.SI-ID: 64314883

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.01.2021

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: mikrovalovi, trikomponentne reakcije, večkomponentna sinteza