Six-minute walk distance in breast cancer survivors : a systematic review with meta-analysis

But-Hadžić, Jasna (author), Dervišević, Mirza (author), Karpljuk, Damir (author), Videmšek, Mateja (author), Dervišević, Edvin (author), Paravlić, Armin (author), Hadžić, Vedran (author), Tomažin, Katja (author)

The six-minute walk test (6MWT) is a widely used test for the indirect measurement of cardiorespiratory fitness in various cancer populations. Although the 6MWT is a simple test, there are no normative values for breast cancer survivors (BCS) or comparisons of results with healthy counterparts. A systematic review with a meta-analysis was carried out, which included studies from 2007 to 2020. Ninety-one studies were found, 21 of which were included in the quantitative synthesis. Among them were 9 randomized controlled trials (RCT), 8 prospective cohort studies and 4 cross-sectional studies. A total of 1084 BCS were included. Our results revealed that healthy subjects (n = 878) covered a significantly greater distance than BCS during the 6MWT (589.9 m vs. 477.4 m, p < 0.001), and the results of the meta-regression analysis showed that the 6MWD was predicted by the participants’ BMI (p < 0.001), but not by their age (p = 0.070). After adjustment for BMI, the healthy subjects also covered greater distances than the BCS (103 m; p < 0.001). The normative values of 6MWT were presented for BCS. Besides, 6MWT distances distinguish between their healthy counterparts, therefore, the 6MWT distance is a relevant parameter for the assessment and monitoring of cardiorespiratory fitness in medical and exercise interventions for BCS.

• Language: English
• Keywords: sport, female, cardio-respiratory fitness, reference values, breast cancer, six minute walk test
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: MF - Faculty of Medicine; FŠ - Faculty of Sport
• Publication status: Published
• Publication version: Version of Record
• Year: 2021
• Number of pages: 13 str.
• Numbering: Vol. 18, iss. 5, art. 2591
• PID: 20.500.12556/RUL-135035
• UDC: 616-006:796.01
• ISSN on article: 1660-4601
• DOI: 10.3390/ijerph18052591
• COBISS.SI-ID: 54053379
• Publication date in RUL: 18.02.2022

Record is a part of a journal

• Title: International journal of environmental research and public health
• Shortened title: Int. j. environ. res. public health
• Publisher: MDPI
• ISSN: 1660-4601
• COBISS.SI-ID: 1818965

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 05.03.2021

Secondary language

• Language: Slovenian
• Keywords: šport, ženske, kardiorespiratorni fitnes, srčno-žilni fitnes, normativne vrednosti, test šestminutne hoje, rak dojk

Projects

• Funder: ARRS - Slovenian Research Agency
• Project number: P5-0147
• Name: Kineziologija monostrukturnih, polistrukturnih in konvencionalnih športov

• Funder: ARRS - Slovenian Research Agency
• Project number: P5-0142
• Name: Bio-psiho-socialni konteksti kineziologije