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Innovative extraction techniques using deep eutectic solvents and analytical methods for the isolation and characterization of natural bioactive compounds from plant material
ID Ivanović, Milena (Author), ID Islamčević Razboršek, Maša (Author), ID Kolar, Mitja (Author)

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Abstract
The growing interest of the food, pharmaceutical and cosmetics industries in naturally occurring bioactive compounds or secondary plant metabolites also leads to a growing demand for the development of new and more effective analysis and isolation techniques. The extraction of bioactive compounds from plant material has always been a challenge, accompanied by increasingly strict control requirements for the final products and a growing interest in environmental protection. However, great efforts have been made in this direction and today a considerable number of innovative extraction techniques have been developed using green, environmentally friendly solvents. These solvents include the deep eutectic solvents (DES) and their natural equivalents, the natural deep eutectic solvents (NADES). Due to their adjustable physical-chemical properties and their green character, it is expected that DES/NADES could be the most widely used solvents in the future, not only in extraction processes but also in other research areas such as catalysis, electrochemistry or organic synthesis. Consequently, this review provided an up-to-date systematic overview of the use of DES/NADES in combination with innovative extraction techniques for the isolation of bioactive compounds from various plant materials. The topicality of the field was confirmed by a detailed search on the platform WoS (Web of Science), which resulted in more than 100 original research papers on DES/NADES for bioactive compounds in the last three years. Besides the isolation of bioactive compounds from plants, different analytical methods are presented and discussed.

Language:English
Keywords:bioactive compounds, plant material, analytical methods, deep eutectic solvents, DES, natural deep eutectic solvents, NADES, innovative extraction techniques, ultrasound-assisted extraction, UAE, microwave-assisted extraction, MAE
Work type:Article
Typology:1.02 - Review Article
Organization:FKKT - Faculty of Chemistry and Chemical Technology
Publication status:Published
Publication version:Version of Record
Year:2020
Number of pages:29 str.
Numbering:Vol. 9, iss. 11, art. 1428
PID:20.500.12556/RUL-134728 This link opens in a new window
UDC:543.64:66.061.3
ISSN on article:2223-7747
DOI:10.3390/plants9111428 This link opens in a new window
COBISS.SI-ID:34155267 This link opens in a new window
Publication date in RUL:27.01.2022
Views:565
Downloads:223
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Record is a part of a journal

Title:Plants
Shortened title:Plants
Publisher:MDPI
ISSN:2223-7747
COBISS.SI-ID:523345433 This link opens in a new window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:01.11.2020

Secondary language

Language:Slovenian
Keywords:bioaktivne komponente, rastlinski material, analizne metode, globoko evtektična topila, naravna globoko evtektična topila, inovativne ekstrakcijske metode

Projects

Funder:Other - Other funder or multiple funders
Funding programme:Slovenia, Ministry of Education, Science and Sport
Project number:OP20.04348

Funder:EC - European Commission

Funder:ARRS - Slovenian Research Agency
Project number:P2-0006
Name:Fizikalno kemijski pojavi na površinskih plasteh in uporaba nanodelcev

Funder:ARRS - Slovenian Research Agency
Project number:P1-0153
Name:Raziskave in razvoj analiznih metod in postopkov

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