Seminiferous epithelium cycle staging based on the development of the acrosome in ram testis

Šturm, Sabina (author), Švara, Tanja (author), Spörndly-Nees, Ellinoir (author), Cerkvenik, Vesna (author), Gombač, Mitja (author), Weber, Anna-Luisa (author), Weber, Klaus (author)

Abstract: Testicular histopathology is considered the most sensitive and reliable method to detect the effects of chemicals on sperm production. To carry out a sensitive examination of testicular histopathology and interpret the changes require knowledge of spermato- genic stages. Spermatogenic staging based on acrosome development during spermiogenesis is conventionally performed in animal species routinely used for research and toxicity testing. In contrast, small ruminants, such as sheep and goats, are rarely used as animal models to evaluate toxicity in male reproductive organs. To the best of our knowledge, a comparable spermatogenic staging system in rams has not yet been fully characterised. Hence, this study aimed to adapt the existing spermatogenic staging based on acrosome development in bull testes to fit the seminiferous epithelium cycle of ram testes. The results show that spermatogenic staging based on acrosome development in bull testes can, with slight modifications, be efficiently used for the staging of ram testes. (

• Language: English
• Keywords: ram, spermatogenesis, staging, acrosome development, spermiogenesis
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: VF - Veterinary Faculty
• Publication status: Published
• Publication version: Version of Record
• Publication date: 07.08.2021
• Year: 2021
• Number of pages: Str. 331-338
• Numbering: Vol. 34, no. 4
• PID: 20.500.12556/RUL-133760
• UDC: 636.09:616
• ISSN on article: 1881-915X
• DOI: 10.1293/tox.2021-0025
• COBISS.SI-ID: 89372163
• Publication date in RUL: 14.12.2021

Record is a part of a journal

• Title: Journal of toxicologic pathology
• Shortened title: J. toxicol. pathol.
• Publisher: Japanese Society of Toxicological Pathology
• ISSN: 1881-915X
• COBISS.SI-ID: 89357315

Licences

• License: CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
• Link: http://creativecommons.org/licenses/by-nc-nd/4.0/
• Description: The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
• Licensing start date: 07.08.2021

Projects

• Funder: ARRS - Slovenian Research Agency
• Project number: P4-0092
• Name: Zdravje živali, okolje in varna hrana

• Funder: ARRS - Slovenian Research Agency
• Funding programme: Postgraduate (PhD) research funding