Analyzing the photoprotection efficiency of sunscreens containing antioxidants under disinfection conditions

Sotler, Robert (author), Adamič, Metka (author), Jarni, Kristjan (author), Gošnak Dahmane, Raja (author), Trebše, Polonca (author), Bavcon Kralj, Mojca (author)

Sunscreens ensure thorough protection against sunburn. The delivery of UV filters into the stratum corneum and viable epidermis could be reduced by the use of antioxidants (such as β-carotene and trans-resveratrol, alone or combined). The presence/absence of antioxidants (trans-resveratrol and β-carotene) in formulations containing benzophenone-3 (UV-filter) and their efficiency under disinfection and neutral conditions are studied and compared. The trial was conducted on 38 people. The prepared ointments were applied to the participants’ forearms, irradiated and monitored by reflectance colorimetry after 0, 4, 6, and 8 min. Descriptive statistics were used to describe the skin color’s main characteristics and the F-ratio was used to test overall differences. The ointments containing antioxidants and benzophenone-3 were the most efficient, followed by those with benzophenone-3 alone. It was proven that photoprotection with benzophenone-3 is still effective, despite the formation of its chlorinated products. Due to the short time of exposure to disinfecting conditions, it could be assumed that benzophenone-3 was only partially chlorinated. This clinical study demonstrated that formulations containing antioxidants are likely to be more suitable for protecting skin against UVB irradiation than a UV filter alone.

• Language: English
• Keywords: ultraviolet radiation, UV filter, benzophenone-3, trans-resveratrol, ß-carotene, chlorinated products
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: ZF - Faculty of Health Sciences; BF - Biotechnical Faculty
• Publication status: Published
• Publication version: Version of Record
• Year: 2021
• Number of pages: 11 str.
• Numbering: Vol. 10, iss. 11, art. 1720
• PID: 20.500.12556/RUL-132560
• UDC: 544.526:614.898:613.165
• ISSN on article: 2076-3921
• DOI: 10.3390/antiox10111720
• COBISS.SI-ID: 82825731
• Publication date in RUL: 29.10.2021

Record is a part of a journal

• Title: Antioxidants
• Shortened title: Antioxidants
• Publisher: MDPI
• ISSN: 2076-3921
• COBISS.SI-ID: 522976025

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 01.11.2021

Secondary language

• Language: Slovenian
• Keywords: ultravijolično sevanje, UV filter, benzofenon-3, trans-resveratrol, ß-karoten, klorirani izdelki

Projects

• Funder: ARRS - Slovenian Research Agency
• Project number: P3-0388
• Name: Mehanizmi varovanja zdravja