A kinetic approach in the evaluation of radical-scavenging efficiency of sinapic acid and its derivatives

Martinović, Neda (avtor), Polak, Tomaž (avtor), Makuc, Damjan (avtor), Poklar Ulrih, Nataša (avtor), Abramovič, Helena (avtor)

A kinetic approach was used to determine the radical scavenging activities of sinapic acid and its derivatives: sinapine, 4-vinylsyringol, syringic acid, syringaldehyde, and ethyl, propyl and butyl sinapate. The responses were expressed as rates of 2,2-diphenyl-1-picrylhydrazyl radical (DPPH$^·$) scavenging (R$_S$), superoxide radical (O$_2$$^{·−}$) scavenging (R$_{FF}$), and β-carotene bleaching in the emulsion system (R$_B$). For R$_S$ and R$_B$, the esters of sinapic acid showed the highest responses while, for R$_{FF}$, this was seen for syringic acid. The effectiveness of the selected compounds for scavenging these free radicals was also determined at a fixed endpoint. The early response parameters were demonstrated to be good discriminators in assessing differences for antioxidants with comparable fixed endpoint activity. The primary feature that ranks the kinetic data and the endpoint determinations is interpreted in terms of the mechanisms of the reactions involved in each of the assays conducted.

• Jezik: Angleški jezik
• Ključne besede: sinapic acid, antioxidant activity, radical scavenging kinetics, radical scavenging mechanisms
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: BF - Biotehniška fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2017
• Št. strani: 17 str.
• Številčenje: Vol. 22, iss. 3, art. 375
• PID: 20.500.12556/RUL-131182
• UDK: 577.1:547.587.53
• ISSN pri članku: 1420-3049
• DOI: 10.3390/molecules22030375
• COBISS.SI-ID: 4761720
• Datum objave v RUL: 23.09.2021

Gradivo je del revije

• Naslov: Molecules
• Skrajšan naslov: Molecules
• Založnik: MDPI
• ISSN: 1420-3049
• COBISS.SI-ID: 18462981

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
• Začetek licenciranja: 01.03.2017

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: organske kisline, fenolne kisline, sinapinske kisline, sinapin, antioksidativna učinkovitost, DPPH, lovilci prostih radikalov

Projekti

• Financer: EC - European Commission
• Program financ.: Erasmus Mundus Action 2
• Naslov: Basileus III

• Financer: ARRS - Agencija za raziskovalno dejavnost Republike Slovenije
• Številka projekta: P4-0121
• Naslov: Biokemijska in biofizikalno-kemijska karakterizacija naravnih snovi