A novel architecture to classify histopathology images using convolutional neural networks

Kandel, Ibrahem (author), Castelli, Mauro (author)

Histopathology is the study of tissue structure under the microscope to determine if the cells are normal or abnormal. Histopathology is a very important exam that is used to determine the patients’ treatment plan. The classification of histopathology images is very difficult to even an experienced pathologist, and a second opinion is often needed. Convolutional neural network (CNN), a particular type of deep learning architecture, obtained outstanding results in computer vision tasks like image classification. In this paper, we propose a novel CNN architecture to classify histopathology images. The proposed model consists of 15 convolution layers and two fully connected layers. A comparison between different activation functions was performed to detect the most efficient one, taking into account two different optimizers. To train and evaluate the proposed model, the publicly available PatchCamelyon dataset was used. The dataset consists of 220,000 annotated images for training and 57,000 unannotated images for testing. The proposed model achieved higher performance compared to the state-of-the-art architectures with an AUC of 95.46%.

• Language: English
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: EF - School of Economics and Business
• Publication version: Version of Record
• Year: 2020
• Number of pages: Str. 1-17
• Numbering: Vol. 10, iss. 8 (art. 2929)
• PID: 20.500.12556/RUL-124233
• UDC: 004:78
• ISSN on article: 2076-3417
• DOI: 10.3390/app10082929
• COBISS.SI-ID: 38419459
• Publication date in RUL: 11.01.2021

Record is a part of a journal

• Title: Applied sciences
• Shortened title: Appl. sci.
• Publisher: MDPI
• ISSN: 2076-3417
• COBISS.SI-ID: 522979353

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 11.01.2021