Functional genetic screens to identify and elucidate potential resistance mechanisms to MTH1 inhibitors : magistrsko delo, magistrski študij - 2. stopnja

Pogačar, Živa (author), Čemažar, Maja (mentor), Evers, Bastiaan (comentor), Ambrožič, Jerneja (reviewer), Sepčić, Kristina (member of the commission for defense)

• Language: English
• Keywords: cancer, targeted therapy, MTH1, ROS, CRISPR, Cas9, functional genetic screen, resistance
• Work type: Master's thesis/paper
• Typology: 2.09 - Master's Thesis
• Organization: BF - Biotechnical Faculty
• Place of publishing: Ljubljana
• Publisher: [Ž. Pogačar]
• Year: 2015
• Number of pages: X f., 79 str.
• PID: 20.500.12556/RUL-123444
• UDC: 577.2(043.2)
• COBISS.SI-ID: 3629647
• Publication date in RUL: 19.12.2020

Secondary language

• Language: Slovenian
• Title: Ugotavljanje mehanizmov odpornosti proti inhibitorjem encima MTH1 s funkcionalnim genetskim pregledom : M. Sc. Thesis, master study programmes
• Keywords: rak, tarčno zdravljenje, MTH1, reaktivne kisikove zvrsti, CRISPR, Cas9, funkcionalni genetski pregled, odpornost