Case report: intoxication in a pig (Sus scrofa domesticus) after transdermal fentanyl patch ingestion

Sredenšek, Jerneja (avtor), Omerzel, Maša (avtor), Lampreht Tratar, Urša (avtor), Kosjek, Tina (avtor), Čemažar, Maja (avtor), Kržan, Mojca (avtor), Seliškar, Alenka (avtor)

An experimental study on the effects of electroporation on pancreatic tissue was performed in pigs, and the fentanyl transdermal patch (FTP) was used postoperatively as part of multimodal pain management. Ingestion of an FTP, which resulted in fentanyl intoxication, was suspected 5 days after placement in one of the experimental pigs. The pig was first dysphoric, running in the stall, panting and vocalizing until it finally became depressed and it remained lying on the floor. Ingestion of an FTP was not observed but the fentanyl plasma concentration on the day of intoxication was 20.7 ng/ml, while at its peak after FTP administration it was only 0.492 ng/ml. The intoxication was successfully treated with a single intramuscular naloxone injection.

• Jezik: Angleški jezik
• Ključne besede: intoxication, pharmacokinetics, naloxone-opioid overdose, swine, pig, fentanyl transdermal patch, pharmacological phenomena, toxicological phenomena, fentanyl
• Vrsta gradiva: Članek v reviji
• Tipologija: 1.01 - Izvirni znanstveni članek
• Organizacija: VF - Veterinarska fakulteta ; MF - Medicinska fakulteta
• Status publikacije: Objavljeno
• Različica publikacije: Objavljena publikacija
• Leto izida: 2020
• Št. strani: 6 str.
• Številčenje: Vol. 7, art. 611097
• PID: 20.500.12556/RUL-122241
• UDK: 636.4.09:616.3:615.9
• ISSN pri članku: 2297-1769
• DOI: 10.3389/fvets.2020.611097
• COBISS.SI-ID: 36219907
• Datum objave v RUL: 30.11.2020

Gradivo je del revije

• Naslov: Frontiers in veterinary science
• Skrajšan naslov: Front. vet. sci.
• Založnik: Frontiers Media
• ISSN: 2297-1769
• COBISS.SI-ID: 3969402

Licence

• Licenca: CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
• Povezava: http://creativecommons.org/licenses/by/4.0/deed.sl
• Opis: To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

• Jezik: Slovenski jezik
• Ključne besede: zastrupitev, farmakokinetika, nalokson-opioidno predoziranje, prašiči