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Model tankega filma na elastičnem substratu za simulacijo ovirane rasti bioloških tkiv
ID Kumer, Nina (Author), ID Brojan, Miha (Mentor) More about this mentor... This link opens in a new window

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Abstract
V magistrski nalogi je obravnavana mehanska stabilnost površine. Teoretični del je razdeljen na dva dela: v prvem je analiziran površinski uklon zaradi ovirane volumetrične rasti tkiva, v drugem pa je obravnavan tlačno obremenjen dvoslojni sistem, sestavljen iz tankega filma, ki leži na debelejšem substratu. Sistem obremenimo na tri različne načine: obremenitev celotne domene, obremenitev filma zaradi rasti filma in obremenitev filma zaradi pred-raztegnjenega substrata. Obravnavani so sistemi z različnimi razmerji togosti med filmom in substratom, beta. Izpeljan je splošen nabor 8 vodilnih enačb za nestabilnost dvoslojnih sistemov, ki ga nadalje skrčimo glede na obravnavan primer. Kot rezultat dobimo kritične deformacije v odvisnosti od razmerja togosti in od normirane valovne dolžine. Za vse primere izvedemo še numerične simulacije v Abaqusu, pri čemer ugotovimo, da se numerični rezultati precej dobro ujemajo z analitičnimi za beta=100 in 10, pri nižjih razmerjih togosti pa so odstopanja zelo velika. Za ravninske primere izvedemo tudi statično strukturno analizo in na podlagi dobljenih podatkov izrišemo grafe, iz katerih je razvidno, kdaj sistem ukloni. Z numerično simulacijo dobimo tudi uklone v več smereh, ki jih analitično ne predvidimo. Na koncu analiziramo še več lastnih oblik, po tem ko površina že ukloni, in ugotovimo, da so si v nekaterih primerih le-te zelo blizu, kar se tiče kritične obremenitve.

Language:Slovenian
Keywords:uklon površine, gubanje, rast, film, substrat, Abaqus
Work type:Master's thesis/paper
Typology:2.09 - Master's Thesis
Organization:FS - Faculty of Mechanical Engineering
Place of publishing:Ljubljana
Publisher:[N. Kumer]
Year:2020
Number of pages:XXII, 54 str.
PID:20.500.12556/RUL-122194 This link opens in a new window
UDC:620.179.11:576.7:004.942(043.2)
COBISS.SI-ID:44263683 This link opens in a new window
Publication date in RUL:26.11.2020
Views:845
Downloads:186
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Secondary language

Language:English
Title:Thin film on elastic substrate as a model for simulation of constrained growth of biological tissues
Abstract:
The mechanical stability of the surface is discussed in this master thesis. The theoretical part is divided into two sections: in the first, surface buckling due to volumetric tissue growth is analyzed, and the second deals with stresses and strains in the two-layer system, which consists of a thin film lying on a thicker substrate. The system is loaded in three different ways: over the entire domain, through a film due to its growth, and by pre-stretching the substrate. Systems with different stiffness ratios between the film and the substrate, beta. A general set of 8 governing equations for the instability of two-layer systems is derived and further reduced depending on the case under consideration. As a result, a relationship for the critical deformation as a function of the stiffness ratio and the normalized wavelength is obtained. We also perform numerical simulations in Abaqus and find that the results are quite consistent with the analytical results for beta=100 and 10, while the deviations become very large at lower ratios. For planar cases we also perform a static structural analysis. Based on the data obtained, we show where the system buckles. The numerical simulations also predict wrinkling in several directions, which are not predicted analytically. Finally, we also analyze some of the eigenmodes and find that in some cases they are very close to each other in terms of critical load.

Keywords:wrinkling, growth, film, substrate, Abaqus

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