Hormoni maščobnega tkiva in njihova vloga pri psih

Šuler, Nika (author), Čebulj Kadunc, Nina (mentor)

Namen naloge je bil predstaviti delovanje hormonov maščobnega tkiva in njihove koncentracije v plazmi pri psih, diagnosticiranih z debelostjo ter predstavitev najpomembnejše bolezni, diabetesa tipa 2, ki nastopi kot posledica debelosti. Debelost je najpogostejša prehranska motnja psov. Čeprav je le-ta posledica energijskega neravnovesja, vplivajo nanjo tudi številni genetski in okoljski faktorji. Do debelosti pride zaradi povečane, s krmo pridobljene energije, in premajhne porabe slednje. Stanje debelosti je zelo pomembno, saj je le ta povezana s hormonskimi in presnovnimi spremembami v telesu. Do hormonskih in presnovnih motenj pride zaradi izločanja adipokinov, oz. biološko aktivnih snovi iz belega maščobnega tkiva, ki so ključni dejavnik pri mnogih bolezenskih stanjih, kot posledica debelosti. Daljša se tudi seznam z debelostjo povezanih bolezni, saj nove študije opisujejo povezave med vnetnimi adipokini in bolezenskimi stanji, kot so osteoartiris, diabetes, respiratorna stiska, hipertenzija, toplotna intoleranca in celo nekatere oblike raka. Ker debelost predstavlja resno presnovno, hormonsko in vnetno motnjo, je preprečevanje in obvladovanje debelosti bistvenega pomena za ohranjanje zdravja psov.

• Language: Slovenian
• Keywords: psi, maščobno tkivo, hormoni, diabetes
• Work type: Bachelor thesis/paper
• Organization: BF - Biotechnical Faculty
• Year: 2020
• PID: 20.500.12556/RUL-120294
• COBISS.SI-ID: 29021187
• Publication date in RUL: 18.09.2020

Secondary language

• Language: English
• Title: Hormones of adipose tissiue and their functions in dogs

Abstract

The aim of B. Sc. Thesis is to present the role of adipose tissue hormones and their concentration in plasma of canines diagnosed with obesity and to present the most important disease, diabetes type 2, which is the consequence of obesity. Obesity is the most common canine nutrition disorder. Even though it is the result of energy imbalance, it is also influenced by multiple genetic and environmental factors. Obesity occurs when increased food-generated energy is not depleted. The obesity level is important since it is connected with hormonal and metabolic changes in the body. Hormonal and metabolic dysfunctions are results of adipokines or other biologically active substances secreted from white fat-tissue. These substances are key factors in multiple diseases that are the result of obesity. The list of diseases linked with obesity is getting longer since new studies show a correlation between inflamed adipocytes and disease states such as osteoarthritis, diabetes, respiratory distress, hypertension, heat intolerance and some forms of cancer. The prevention and management of obesity is essential for keeping canines healthy because it presents a serious metabolic, hormonal and inflamed dysfunction.

• Keywords: dogs, adipose tissue, hormones, diabetes