Molekulski mehanizem vezave [alfa]-sinukleina na lipidne membrane : doktorska disertacija

Pirc, Katja (author), Poklar Ulrih, Nataša (mentor), Pogačnik da Silva, Lea (co-mentor)

• Language: Slovenian
• Keywords: [alfa]-sinuklein, Parkinsonova bolezen, proteini, agregacija, fibrilacija, točkovne mutacije, tirozin, strukturne lastnosti, modelne lipidne membrane, lipidni dvosloj, CD spektroskopija, fluorescenčna anizotropija, diferenčna dinamična kalorimetrija, ureditveni parameter, krvno-možganska pregrada, flavonoidi, nikotin, nevroprotektivnost
• Work type: Dissertation
• Typology: 2.08 - Doctoral Dissertation
• Organization: BF - Biotechnical Faculty
• Place of publishing: Ljubljana
• Publisher: [K. Pirc]
• Year: 2015
• Number of pages: XVII f., 127, [6] str.
• PID: 20.500.12556/RUL-116471
• UDC: 577.24+577.352:616.8
• URN: URN:NBN:SI:doc-7AIS2GJM
• COBISS.SI-ID: 4507000
• Publication date in RUL: 24.05.2020

Secondary language

• Language: English
• Title: The molecular mechanism of [alpha]-synuclein binding to model lipid membranes
• Keywords: [alpha]-synuclein, Parkinsonʼs disease, proteins, aggregation, fibrillation, point mutations, tyrosin, structural properties, model lipid membranes, lipid bilayer, CD spectroscopy, fluorescent anisotropy, differential scanning calorimetry, order parameter, blood-brain barrier, flavonoids, nicotin, neuroprotection