Introduction: Marijuana is one of the most commonly used illegal drugs. It's usage is rising, even among pregnant women. Marijuana crosses the barriers of the placenta and the mother's milk. Purpose: The purpose of this diploma work is to access and analize the available data of marijuana effects on the mother and fetus. We aim to confirm or deny these research statements: 1. Marijuana is used in 10% of pregnant women, who are younger and less educated. 2. Marijuana in pregnancy is not related to gestational diabetes or gestational hypertension. 3. Marijuana in pregnancy is related to growth restriction of the fetus and premature labour. It is also the purpose of this diploma work to make informative handouts for medical workers and pamphlets for women. Methods: A literature review was made, with the time frame from August 2018 to April 2019. The search was conducted in English with these keywords: marijuana in pregnancy, cannabis in pregnancy, prenatal marijuana, prenatal cannabis, effects on mother, effects on fetus. Results: The usage of marijuana in pregnancy ranges fro 2-30 %. Women, who use it are often smokers, have a lower socioeconomic status, are younger and more often single. A connection between marijuana use in pregnancy and lower birth weight, premature labour, care in the NICU, infections of the newborn and stillbirth was shown. A connection between marijuana use in pregnancy and gestational diabetes and gestational hypertension was not shown. Long term effects on fetus are attention disorders, disorders in saving, processing and usage of data and disorders of short term memory. Structure of the brain is also altered. The children of mothers who used marijuana in pregnancy have started using marijuana earlier. Discussion and conclusion: Women who use marijuana in pregnancy belong to a vulnerable group of women, which can have independent effects on pregnancy and the fetus. The use of marijuana is rising, as is its potency, so a safe limit cannot be proposed. Healthcare workers play an important role in educating the public about possible effects of marijuana use in pregnancy and to provide the best possible care for women who are using marihuana during pregnancy.
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