Vpliv črevesne mikrobiote na organizem

Gomboc, Zala (author), Glavan, Gordana (mentor)

V zadnjem času narašča število raziskav v povezavi s črevesno mikrobioto in vplivom na naše telo. Črevesna mikrobiota je kompleksna skupnost mikroorganizmov. Večina mikroorganizmov je bakterij, in sicer so najpogostejši predstavniki bakterij iz družin Bacteroidaceae, Clostridiaceae, Prevotellacaeae, Eubacteriaceae, Ruminococcaceae, Bifidobacteriaceae, Lactobacillaceae, Enterobacteriaceae. V nalogi smo se osredotočili na razvoj črevesne mikrobiote in dejavnike, ki pri tem sodelujejo. Nato smo naredili pregled najbolj raziskanih povezav črevesne mikrobiote in bolezni. In sicer odnos črevesne mikrobiote in imunskega sistema, vpliv črevesne mikrobiote na centralni živčni sistem, metabolizem, raka (koloretalni rak, rak želodca, rak na požiralniku), kardiovaskularne bolezni in na bolezni jeter ter ledvic. Pomembno je vzročno-posledično razmerje med črevesno mikrobioto in patofizološkimi spremembami, kar do sedaj še ni dobro opredeljeno. V prihodnosti bodo raziskave usmerjene v iskanje novih zdravstvenih intervencij s pomočjo razumevanja vpliva črevesne mikrobiote na zdravje ljudi.

• Language: Slovenian
• Keywords: črevesna mikrobiota, bakterije, disbioza, razvoj črevesne mikrobiote, imunost, alergije, centralni živčni sistem, debelost, diabetes mellitus
• Work type: Bachelor thesis/paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: BF - Biotechnical Faculty
• Publisher: [Z. Gomboc]
• Year: 2018
• PID: 20.500.12556/RUL-102780
• UDC: 612.33:579.2:61
• COBISS.SI-ID: 4942968
• Publication date in RUL: 08.09.2018

GOMBOC, Zala, 2018, Vpliv črevesne mikrobiote na organizem [online]. Bachelor’s thesis. Z. Gomboc. [Accessed 5 April 2025]. Retrieved from: https://repozitorij.uni-lj.si/IzpisGradiva.php?lang=eng&id=102780

Secondary language

• Language: English
• Title: Effect of gut microbiota on organism

Abstract

Recently, there has been an increase in the number of studies in association with intestinal microbiota and its effect on our body. Intestinal microbiota is a complex community of microorganisms. Most of the microorganisms are bacteria, including the representatives of most common family Bacteroidaceae, Clostridiaceae, Prevotellacaeae, Eubacteriaceae, Ruminococcaceae, Bifidobacteriaceae, Lactobacillaceae, Enterobacteriaceae. In our work we focused on the development of intestinal microbiota and the factors that influence this development. An overview of the most explored links between the intestinal microbiota and diseases was made. In particular, the relationship of the intestinal microbiota and the immune system, the effect of intestinal microbiota on the central nervous system, metabolism, cancer (colorectal cancer, gastric and esophageal), cardiovascular diseases, liver and kidney diseases were described. The causal and consequential relationship between intestinal microbiota and pathophysiological changes is important, but it is not yet well understood. In the future, research will be focused on finding new medical interventions by understanding the impact of intestinal microbiota on human health.

• Keywords: gut microbiota, bacteria, dysbiosis, development of gut microbiota, immunity, allergies, central nervous system, obesity, diabetes mellitus