Pomen ustrezne prehrane za živali v poskusih

Grum, Barbara (author), Pirman, Tatjana (mentor)

Raziskovalci že vrsto let uporabljajo poskusne živali tako za raziskovalne (medicina, biologija) namene kot tudi za različna testiranja npr. v farmaciji. Zato, da lahko izvajalci poskusa kar najbolje sledijo pravilu 3-R, ki temelji na zmanjšanju števila živali v poskusu (reduction), izboljšanju zasnove in izvedbe poskusa (refinement) ter zamenjavi živali z nižje razvitimi živalmi, modeli, ali in vitro poskusi (replacement), morajo biti genetika živali in okoljski dejavniki, ki lahko močno vplivajo na izvedbo poskusa, kar najbolje nadzorovani. Eden izmed takšnih dejavnikov je tudi prehrana poskusnih živali. Ta pomembno vpliva na rast in razvoj živali, njihovo počutje, obnašanje ter zdravstveno stanje. Če prehrana negativno vpliva na katero izmed teh lastnosti, lahko to močno spremeni zanesljivost rezultatov poskusa. Za ustrezno izvedbo poskusa, ki bo doprinesel rezultate, ki temeljijo na željenemu dejavniku in ne na prehrani, moramo izbrati krmo, ki nam bo to zagotovila, poleg tega pa bo kar najbolje ustrezala potrebam izbranih živali.

• Language: Slovenian
• Keywords: poskusne živali, prehrana živali
• Work type: Bachelor thesis/paper
• Organization: BF - Biotechnical Faculty
• Year: 2018
• PID: 20.500.12556/RUL-101992
• COBISS.SI-ID: 4108168
• Publication date in RUL: 19.07.2018

Secondary language

• Language: English
• Title: The importance of suitable diet for the animals in experiment

Abstract

Researchers have been using laboratory animals in science experiments (medicine, biology) and testings (pharmacy) for many years. To follow the 3-R rule which stands for reduction, refinement and replacement of the animals in experiments their genetic profile and environmental factors have to be as controlled as possible because they can have a great effect on research results. Nutrition is one of those factors and it can play a major role in animal’s development, growth, well-being, behaviour and health. Negative effects of nutrition on any of these characteristics can cause lower reliability of experimental results. To make sure that results depend only on factors that researchers want them to depend on and not on nutrition they have to choose a diet that will reassure that and besides be the most appropriate diet for chosen animals.

• Keywords: laboratory animals, animal nutrition