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2. Simulation- and AI-directed optimization of 4,6-substituted 1,3,5-triazin-2(1H)-ones as inhibitors of human DNA topoisomerase IIαBarbara Herlah, Tjaša Goričan, Nika Strašek Benedik, Simona Golič Grdadolnik, Izidor Sosič, Andrej Perdih, 2024, original scientific article Keywords: molecular design, molecular simulations, deep learning, human DNA, topoisomerase IIα, catalytic inhibitors, anticancer agents Full text (file, 10,65 MB) This document has more files! More... |
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6. Sinteza in vrednotenje novih derivatov 4,6-substituiranih-1,3,5-triazin-2(1H)-onov kot katalitičnih zaviralcev človeške DNA topoizomeraze IIαAnja Pavlovič, 2021, master's thesis/paper Keywords: rak, človeška DNA topoizomeraza IIα, katalitični zaviralci, 4, 6-substituirani-1, 3, 5-triazin-2(1H)-oni Full text (file, 3,26 MB) |
7. Selective DNA gyrase inhibitorsTihomir Tomašič, Asta Zubrienė, Žiga Skok, Riccardo Martini, Stane Pajk, Izidor Sosič, Janez Ilaš, Daumantas Matulis, Sharon D. Bryant, 2021, original scientific article Keywords: antibacterial, ATP-competitive, DNA gyrase, Hsp90, pharmacophore model, topoisomerase II, target activity profiling, topoisomerase IIα Full text (file, 6,96 MB) This document has more files! More... |
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9. Strukturno podprto načrtovanje in sinteza 4,6-substituiranih 1,3,5-triazin-2(1H)-onov kot katalitičnih zaviralcev človeške DNA-topoizomeraze IIαGašper Grošelj, 2023, master's thesis/paper Keywords: rak, človeška DNA topoizomeraza IIα, katalitični zaviralci, 4, 6-substituirani-1, 3, 5-triazin-2(1H)-oni Full text (file, 3,33 MB) |