The thesis addresses the earthquake resistance of the typical masonry apartment building constructed in the 1960s in Škofja Loka. In the first part the seismic response of masonry buildings is presented. Explained are the models of three possible masonry wall failure mechanisms, which are the basis for determining the capacity of single walls taking into account the shear failure due to formation of diagonal cracks, the sliding shear failure and the flexural failure. The definition of the design seismic action and fundamentals of the pushover analysis follow. The second part of the thesis deals with performance assessment of masonry building in Škofja Loka. The seismic demand is firstly assessed by using the lateral force method. Material characteristics were defined according to design project with consideration of provisions of Eurocode standard. Only ground floor is included in seismic performance assessment since it is the most vulnerable. The effects of the concrete basement were neglected in the analysis. The results of the analysis according to Eurocode 6 and 8 have shown that the building meets safety requirements in longitudinal direction, but not in the case of transverse direction. Conclusions on the basis of elastic analysis were confirmed by simplified nonlinear pushover analysis. At the last part of the thesis a comparison between design seismic action according to standard Eurocodes and regulations from 1964, which were the consequence of the catastrophic Skopje Eartquake, are presented. It was found that Eurocode provided the 2,5 times greater design seismic action.