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Human papillomavirus (HPV) prevalence and HPV type distribution in cervical, vulvar, and anal cancers in central and eastern Europe
Škamperle, Mateja (Avtor), Kocjan, Boštjan (Avtor), Maver Vodičar, Polona (Avtor), Seme, Katja (Avtor), Poljak, Mario (Avtor)

URLURL - Predstavitvena datoteka, za dostop obiščite http://www.acta-apa.org/ Novo okno

Izvleček
Introduction: High-risk human papillomaviruses (HPV) play the leading etiological role in the development of cervical, anal, and vaginal cancers and a substantial proportion of penile, vulvar, and oropharyngeal (tonsillar) cancers. Methods: The article summarizes the results of the most important studies that examined tissue specimens of cervical, anal, and vulvar carcinoma from 16 central and eastern European countries for the presence of HPV DNA. Results: Twenty-eight eligible studies were identified. Among 2,531 invasive cervical cancers, 86.6% were HPV-positive. The combined prevalence of HPV-16/18 among HPV-positive cervical cancers was 87.5%. The overall prevalence of HPV DNA in six studies of anal carcinomas (43 cases) and vulvar carcinomas (164 cases) was 90.7% and 32.9%, respectively. HPV-16 DNA was detected in 86% of all anal carcinomas studied, and the proportion of HPV-16 positive vulvar carcinomas varied from 10.9% to 27.5%. HPV-18 DNA was not detected in any anal or vulvar carcinoma studied. Conclusions: HPV prevalence and type distribution among women with cervical cancer in central and eastern Europe is comparable with other European regions. Several gaps in knowledge exist in the region concerning HPV prevalence and type distribution among women with HPV-related cancers other than cervical cancer and in the general population.

Jezik:Angleški jezik
Ključne besede:HPV virusi, razvoj raka, diagnostika, centralna in vzhodna Evropa
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:MF - Medicinska fakulteta
Leto izida:2013
Založnik:Slovene Welding Society
Št. strani:str. 1-5
Številčenje:Vol. 22, no. 1
UDK:578
ISSN pri članku:1318-4458
DOI:10.2478/v10162-012-0024-1 Povezava se odpre v novem oknu
COBISS.SI-ID:30626009 Povezava se odpre v novem oknu
Število ogledov:595
Število prenosov:129
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
 
Skupna ocena:(0 glasov)
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Gradivo je del revije

Naslov:Acta dermatovenerologica Alpina, Panonnica et Adriatica
Skrajšan naslov:Acta dermatovenerolog. Alp. Panon. Adriat.
Založnik:Slovene Welding Society
ISSN:1318-4458
COBISS.SI-ID:31649024 Novo okno

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