The quaternary aquifers in the Pomurje region are among the most vulnerable and polluted in Slovenia. In addition to human impact, the vulnerability and pollution of aquifers depend on the geological composition. In the master's thesis, univariate and bivariate statistical and geostatistical analyses were used and the chemical status of groundwater was assessed in the Pomurje region. Data on water cycle variables for the period 1992-2008 were statistically analysed and evaluated. The geostatistical analysis was based on the thicknesses and lithology of low permeable layers, which lie on the quaternary sandy -gravely highly permeable aquifer, deposited by the Mura river and its tributaries. The results indicate that upper low - permeable layers have a great impact on the pollution of aquifers in the Pomurje region. They affect the variability of variables, relationships between them, and the chemical status of groundwater. Variables of groundwater quality show higher variety. The thicknesses and lithological characteristics of these layers dictate the hydrodynamic characteristics of the aquifer. Unconfined aquifer, which is transitioning into leaky aquifer, is the most vulnerable and polluted in the central part of Pomurje region. On the aquifer's lateral boundaries upper low - permeable layers are thicker. The extent of groundwater pollution is reduced, concentrations of pollutants are lower. The analysis of linear trends has shown that pollutants concentrations are decreasing for observed period, and the chemical status of groundwater in the Pomurje is improving.