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Elektroporacija
Maček Lebar, Alenka (Avtor), Serša, Gregor (Avtor), Čemažar, Maja (Avtor), Miklavčič, Damijan (Avtor)

URLURL - Predstavitvena datoteka, za dostop obiščite http://www.dlib.si/details/URN:NBN:SI:DOC-20ECIBQI Povezava se odpre v novem oknu

Izvleček
Electroporation is a process, which causes transient high-permeability of the cell membrane due to application of electric field. In the state of high-permeability, membrane allows different kinds of small and large molecules to be introduced into the cytoplasm, although the cell plasma membrane represents a formidable barrier for them in its normal state. Electroporation is governed by many parameters. Parameters of applied electricfield which affect electroporation are the electric field strength, number of pulses, duration of each pulse and applied frequency. Electroporation is also affected by other parameters such as temperature, conductivity of the poration medium, osmotic pressure and cytoskeleton integrity. Transient high-permeability state induced by applied electric fieldcan be obtained on each and every cell, it does not affect cell viability, it does not affect cell organels and causes minimal irregularities in membrane functions. Therefore, applicability of electroporation is wide. Itis a phenomenon which is already widely used in biotechnology cell biology and its importance in clinical practice is growing.

Jezik:Slovenski jezik
Ključne besede:elektroporacija, genska terapija, zdravljenje z zdravili
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:FE - Fakulteta za elektrotehniko
Leto izida:1998
Št. strani:str. 339-354
Številčenje:Let. 37
UDK:576
ISSN pri članku:0025-8121
COBISS.SI-ID:1346388 Povezava se odpre v novem oknu
Število ogledov:480
Število prenosov:77
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
 
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Gradivo je del revije

Naslov:Medicinski razgledi
Skrajšan naslov:Med. razgl.
Založnik:Medicinski razgledi
ISSN:0025-8121
COBISS.SI-ID:3390978 Povezava se odpre v novem oknu

Sekundarni jezik

Jezik:Angleški jezik
Naslov:Electroporation
Ključne besede:electroporation, gene therapy, drug therapy

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