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Farmakoekonomika zdravil za zdravljenje Alzheimerjeve in Parkinsonove bolezni
Obradović, Marko (Author)

URLURL - Presentation file, Visit http://www.dlib.si/details/URN:NBN:SI:doc-OLJK9PZY This link opens in a new window

Abstract
V uvodu je jedrnato predstavljena metodologija farmakoekonomskih raziskav. Temu sledijo izsledki raziskav, ki so ocenjevale ekonomske posledice obeh bolezni za družbo, ter trenutne informacije, ki so na voljo o klinični in stroškovni učinkovitosti zdravil za zdravljenje Alzheimerjeve in Parkinsonove bolezni. Raziskave kažejo, da je družbeno breme Alzheimerjeve in Parkinsonove bolezni veliko. Bolezni mooeno vplivata ne zgolj na bolnike, temveč tudi na njihove skrbnike. Letni stroški na bolnika z Alzheimerjevo oz.Parkinsonovo boleznijo izredno narastejo, kadar se stanje bolnika poslabša.Obstoječa zdravila, ki se uporabljajo za zdravljenje Alzheimerjeve bolezni, imajo skromne učinke. Trenutno primanjkuje raziskav, ki bi vrednotile vpliv teh zdravil na kakovost življenja bolnikov in skrbnikov, kar onemogoča sprejetje oprijemljivih zaključkov o stroškovni učinkovitosti teh zdravil. Pri zdravljenju Parkinsonove bolezne je klinično pomembna učinkovitost zdravil dokazana, kljub temu pa obstaja potreba po večjih in dolgotrajnejših kliničnih raziskavah. Obstoječe farmakoekonomske analize kažejo, da novejša zdravila za zdravljenje Parkinsonove bolezni kljub dodatnim stroškom za zdravila potencialno znižajo celokupne stroške z družbenega vidika.

Language:Slovenian
Keywords:Alzheimerjeva bolezen, Parkinsonova bolezen, zdravljenje, farmakoekonomika, družbeno breme
Work type:Not categorized (r6)
Tipology:1.08 - Published Scientific Conference Contribution
Organization:FFA - Faculty of Pharmacy
Year:2008
Publisher:Slovensko farmacevtsko društvo
Number of pages:str. 90-98
Numbering:59, 2
UDC:615.2
ISSN on article:0014-8229
COBISS.SI-ID:2326129 Link is opened in a new window
Views:581
Downloads:168
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Record is a part of a proceedings

Title:Simpozij ob 33. skupščini Slovenskega farmacevtksega društva, Portorož, 15.5 - 17.5.2008
COBISS.SI-ID:2331505 This link opens in a new window

Record is a part of a journal

Title:Farmacevtski vestnik
Shortened title:Farm. vestn.
Publisher:Slovensko farmacevtsko društvo
ISSN:0014-8229
COBISS.SI-ID:3105794 This link opens in a new window

Secondary language

Language:English
Title:Pharmacoeconomics of drugs used in the treatment of Alzheimer's and Parkinson's disease
Abstract:
Methodology used in pharmacoeconomic research is briefly described in the introductory section, followed by the results of cost-ofillness studies and present information on clinical effectiveness and cost-effectiveness of drugs used in the treatment of Alzheimerćs and Parkinsonćs disease. Studies show that the burden of Alzheimerćs and Parkinsonćs disease is substantial. Not only patients but also caregivers are strongly affected by the diseases. Yearly costs per patient with Alzheimerćs or Parkinsonćs disease increase sharply as disease progresses. Presently available drugs for the treatment of Alzheimerćs disease show only modest effect. Moreover, there is a lack of research evaluating the effect of drugs on the quality of life of these patients, so no firm conclusions about the cost-effectiveness of these drugs can be reached. Effectiveness of drugs used in the treatment of Parkinsonćs disease is clinically relevant, nevertheless, large and long-term studies are needed. The existing pharmacoeconomics studies show that from societal perspective, additional cost of new drugs for the treatment of Parkinsonćs disease is potentially outweighted by other savings.


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