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Razvoj zaživljenjske diagnostike bolezenskih beljakovinskih odlag v možganih: prionske bolezni : komentar
Šmid, Lojze (Author), Bresjanac, Mara (Author)

URLURL - Presentation file, Visit http://www.dlib.si/details/URN:NBN:SI:doc-SGYI0QQW This link opens in a new window

Abstract
Translational medicine is a term describing systematic efforts for adequate testing and transfer of basic research findings into dinical practice. The paper outlines a series of studies aimed at evaluating adiagnostic potential of positron emission tomography with a radioisotope probe (18F)FDDNP for earlyrecognition of pathologic protein deposits in the brain s of prion disease patients. Slovene scientists contributed significantly to all studies in this bench-to-bedside sequence of translational neuroscience.

Language:Slovenian
Work type:Not categorized (r6)
Tipology:1.04 - Professional Article
Organization:MF - Faculty of Medicine
Year:2011
Publisher:Slovensko zdravniško društvo
Number of pages:str. 971-974
Numbering:Letn. 80, št. 12
UDC:616.9
ISSN on article:1318-0347
COBISS.SI-ID:29310425 Link is opened in a new window
Views:404
Downloads:105
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Record is a part of a journal

Title:Zdravniški vestnik
Publisher:Slovensko zdravniško društvo
ISSN:1318-0347
COBISS.SI-ID:32893696 This link opens in a new window

Secondary language

Language:English
Title:Development of in vivo diagnosis of pathologic protein deposits in the brains of prion disease patients
Abstract:
Translacijska medicina obsega sistematična prizadevanja za ustrezno preverbo in prenos raziskovalnih spoznanj temeljnih raziskav v uporabno medicinsko prakso. Prispevek orisuje raziskave diagnostične uporabnosti pozitronske izsevne tomografije z radioizotopsko označenim molekulskim sledilcem š18FđFDDNP za zgodnjo zaživljenjsko prepoznavo bolezenskih beljakovinskih odlag v možganih bolnikov s prionskimi boleznimi. Raziskave, v katerih imajo pomembno vlogo tudi slovenski znanstveniki, so peljale od laboratorijskih poskusov do klinične študije in predstavljajo dober primer translacijske nevroznanosti.


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