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Numerical simulation of two-phase flow in a Wurster coating chamber and comparison with experimental results
Šibanc, Rok (Avtor), Srčič, Stanko (Avtor), Dreu, Rok (Avtor)

URLURL - Predstavitvena datoteka, za dostop obiščite http://www.sciencedirect.com/science/article/pii/S0009250913003965 Novo okno

Izvleček
Pellet coating is commonly performed in a fluid bed coater such as a Wurster coater. Computational fluid dynamics (CFD) simulations and experimental measurements of laboratory-scale Wurster coating were performed. CFD simulations were performed in a 2D axisymmetric space using the two-fluid model. The effect of the Wurster gap and fluidizing air flow rate on gas-solidflow was analyzed in both simulations and experiments. Experimentally, the draft tube two-phase flow was evaluated by measuring the volume fraction of pellets within the draft tube and local particle velocities at the tube exit and by monitoring the local pressure drop fluctuations. A rather good agreement between the simulated and experimental results was observed and thus it can be assumeed that this particular simulation setup represents a computationally reasonable tool that provides a valuable insight into the Wurster coating process due to the impact of two-phase flow properties on the process.

Jezik:Angleški jezik
Ključne besede:Wursterjeva komora, pelete, farmacevtska tehnologija, tehnologija delcev, pomožne snovi, multifazni pretok
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:FFA - Fakulteta za farmacijo
Leto izida:2013
Št. strani:str. 225-237
Številčenje:Vol. 99
UDK:661.12
ISSN pri članku:0009-2509
DOI:10.1016/j.ces.2013.05.057 Povezava se odpre v novem oknu
COBISS.SI-ID:3474033 Povezava se odpre v novem oknu
Število ogledov:368
Število prenosov:70
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
 
Skupna ocena:(0 glasov)
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Gradivo je del revije

Naslov:Chemical Engineering Science
Skrajšan naslov:Chem. eng. sci.
Založnik:Pergamon Press
ISSN:0009-2509
COBISS.SI-ID:838916 Novo okno

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