izpis_h1_title_alt

CTSS activation coexists with CD40 activation in human atheroma : evidence fromplasma mRNA analysis
Černe, Darko (Author), Štern, Irma (Author), Marc, Janja (Author), Černe, Andreja (Author), Zorman, Darko (Author), Kržišnik-Zorman, Simona (Author), Kranjec, Igor (Author)

URLURL - Presentation file, Visit http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TDD-51X1VSJ-5&_user=4776866&_coverDate=04%2F30%2F2011&_alid=1683914077&_rdoc=1&_fmt=high&_orig=search&_origin=search&_zone=rslt_list_item&_cdi=5196&_sort=r&_st=13&_docanchor=&view=c&_ct=1&_acct=C000033658&_version=1&_urlVersion=0&_userid=4776866&md5=2c2ce08b316b2c6c7962876ffdf12afb&searchtype=a New window

Abstract
Objectives: By the analysis of plasma mRNA levels, we tested the hypothesis that, in human atheroma, CTSS activation coexists with activation of CD40. Design and methods: mRNAs were isolated from plasma of patients with coronary atherosclerosis and quantified by real-time RT-PCR. Results: CTSS mRNA levels correlated with CD40 mRNA levels, independently of observed traditional risk factors for atherosclerosis and pharmacological treatment. Conclusions: Our results suggest that CTSS mediated atherogenesis may be associated with a CD40 mediated inflammatory and immune response. Further invasive atheroma analysis is reasonable.

Language:English
Keywords:mRNA, plazma, CTSS, CD40, ateroskleroza
Work type:Not categorized (r6)
Tipology:1.03 - Short Scientific Article
Organization:FFA - Faculty of Pharmacy
Year:2011
Number of pages:str. 438-440
Numbering:Vol. 44, iss. 5/6
UDC:616.1
ISSN on article:0009-9120
COBISS.SI-ID:2974577 Link is opened in a new window
Views:391
Downloads:112
Metadata:XML RDF-CHPDL DC-XML DC-RDF
 
Average score:(0 votes)
Your score:Voting is allowed only to logged in users.
:
Share: Bookmark and Share

Record is a part of a journal

Title:Clinical biochemistry
Shortened title:Clin. biochem.
Publisher:Elsevier.
ISSN:0009-9120
COBISS.SI-ID:22275033 New window

Similar documents

Similar works from RUL:
Similar works from other Slovenian collections:

Comments

Leave comment

You have to log in to leave a comment.

Comments (0)
0 - 0 / 0
 
There are no comments!

Back