Evaluation of pulpal blood flow during orthodontic space closure : prospective clinical trial

Golež, Aljaž (author), Ovsenik, Maja (author), Cankar, Ksenija (author)

Introduction: Orthodontic tooth movement (OTM) is a biological process that can affect the vascularization of the dental pulp. The forces exerted on the teeth may increase periapical pressure that could compress the arterioles, which in turn affects pulpal blood flow (PBF). The study aimed to investigate how OTM affects PBF during orthodontic space closure. Methods: A total of 22 adolescent participants who required orthodontic space closure in mandibular posterior sectors were enrolled in a prospective clinical study. The same sliding mechanics, wires, and active elements were used. Patients were observed before OTM, after leveling before space closure, and at the 4th, 7th, 21st, and 28th during active space closure. PBF was measured with laser Doppler (LD) flowmetry. Dental models were obtained with an intraoral scanner. Results: The LD flow values decreased significantly during the observation period (2-way repeated measures analysis of variance, P <0.001). There was a significant difference in LD flow between tooth categories (2-way repeated measures analysis of variance, P <0.001). During space closure, the most pronounced LD flow reduction was observed in single-rooted teeth closest to the residual space. A higher speed of OTM was associated with a greater decrease in LD flow on day 4 of OTM (Pearson correlation, P = 0.0299). Conclusions: Orthodontic space closure reduced PBF; it was lowest in the early stages of space closure and showed a tendency to increase during the first month. Anterior teeth closer to the interdental space that experiences more OTM and teeth that move faster during initial OTM had a higher risk of reduced blood flow.

• Language: English
• Keywords: pulpal blood flow, evaluation, prospective clinical trail, orthodontics
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: MF - Faculty of Medicine
• Publication status: Published
• Publication version: Version of Record
• Year: 2024
• Number of pages: Str. 549-560.e6
• Numbering: Vol. 166, iss. 6
• PID: 20.500.12556/RUL-165163
• UDC: 616.31
• ISSN on article: 0889-5406
• DOI: 10.1016/j.ajodo.2024.07.017
• COBISS.SI-ID: 206521859
• Publication date in RUL: 25.11.2024

Record is a part of a journal

• Title: American journal of orthodontics and dentofacial orthopedics
• Shortened title: Am. j. orthod. dentofacial. orthop.
• Publisher: American Association of Orthodontists, Elsevier
• ISSN: 0889-5406
• COBISS.SI-ID: 24929536

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: krvni pretok pulpe, vrednotenje, prospektivno klinično preskušanje, ortodontija

Projects

• Funder: ARIS - Slovenian Research and Innovation Agency
• Project number: P3-0019
• Name: Aplikativna in bazična fiziologija in patofiziologija v medicini

• Funder: ARIS - Slovenian Research and Innovation Agency
• Project number: J3-50103
• Name: Vpliv ortodontskega premika zoba na stanje zobne pulpe