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1. Nucleotide-binding oligomerization domain 1/Toll-like receptor 4 co-engagement promotes non-specific immune response against K562 cancer cells
Samo Guzelj, Žiga Jakopin, 2022, original scientific article

Keywords: NOD1 agonist, TLR4 agonist, LPS, synergy, cytolytic activity, PBMC, NK cells, K562
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2. Development of novel NOD2 agonists and dual NOD2 and TLR7 agonists as vaccine adjuvants
Samo Guzelj, 2022, doctoral dissertation

Keywords: conjugates, desmuramylpeptides, immune synergy, immunomodulation, NOD2, pattern recognition receptors, TLR7, vaccine adjuvants
Full text (file, 23,63 MB)

3. Discovery of desmuramylpeptide NOD2 agonists with single-digit nanomolar potency
Samo Guzelj, Špela Janež, Žiga Jakopin, 2022, original scientific article

Keywords: NOD2, desmuramylpeptide, immunostimulant, adamantane, PBMC cytotoxicity, K562, agonists, cells, peptides and proteins, reaction products, toxicological synergy
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