1. Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drugTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Jakob Kljun, Iztok Turel, Evelyne Benoit, Robert Frangež, 2020, original scientific article Keywords: organoruthenium nitrophenanthroline complex, acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, mouse neuromuscular system, ruthenium, muscle relaxation, physiology, glutathione transferase Full text (file, 1,45 MB) This document has more files! More... |
2. Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probesStane Pajk, Damijan Knez, Urban Košak, Maja Zorović, Xavier Brazzolotto, Nicolas Coquelle, Florian Nachon, Jacques-Philippe Colletier, Marko Živin, Jure Stojan, Stanislav Gobec, 2020, original scientific article Keywords: butyrylcholinesterase, inhibitor, probe, fluorescence Full text (file, 1,60 MB) This document has more files! More... |
3. Treatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitorMaja Zakošek, Sonja Prpar Mihevc, Malan Štrbenc, Urban Košak, Ilija German Ilić, Jurij Trontelj, Simon Žakelj, Stanislav Gobec, Darja Pavlin, Gregor Majdič, 2021, original scientific article Keywords: Alzheimer’s disease, butyrylcholinesterase, butyrylcholinesterase inhibitor, canine cognitive dysfunction, canine dementia scale, dogs Full text (file, 1,34 MB) This document has more files! More... |
4. Structural isomerism and enhanced lipophilicity of pyrithione ligands of organoruthenium(II) complexes increase inhibition on AChE and BuChEJerneja Kladnik, Samuel Ristovski, Jakob Kljun, Andrea Defant, Ines Mancini, Kristina Sepčić, Iztok Turel, 2020, original scientific article Keywords: Alzheimer’s disease, acetylcholinesterase, butyrylcholinesterase, cholinesterase inhibitor, molecular docking, organoruthenium(II) complexes, pyrithione derivatives Full text (file, 1,28 MB) This document has more files! More... |
5. 4-phenethyl-1-propargylpiperidine-derived dual inhibitors of butyrylcholinesterase and monoamine oxidase BTjaša Mazej, Damijan Knez, Anže Meden, Stanislav Gobec, Matej Sova, 2021, original scientific article Keywords: Alzheimer's disease, butyrylcholinesterase, monoamine oxidase B, inhibitors, multi-target-directed ligands, multifunctional ligands Full text (file, 3,88 MB) This document has more files! More... |
6. Polyfunctionalized α-phenyl-tert-butyl(benzyl)nitronesDaniel Diez-Iriepa, Damijan Knez, Stanislav Gobec, Isabel Iriepa, Cristóbal de los Ríos, Isaac Bravo, Francisco López-Muñoz, José Marco-Contelles, Dimitra Hadjipavlou-Litina, 2022, original scientific article Keywords: butyrylcholinesterase, free radical scavengers, neuroprotection, α-phenyl-tert-butyl(benzyl)nitrones, in vitro digestion, extractable and bound phenolics Full text (file, 2,12 MB) This document has more files! More... |
7. From tryptophan-based amides to tertiary aminesAnže Meden, Damijan Knez, Xavier Brazzolotto, Florian Nachon, Jose Dias, Jurij Svete, Jure Stojan, Uroš Grošelj, Stanislav Gobec, 2022, original scientific article Keywords: cholinesterase inhibitors, Alzheimer's disease, butyrylcholinesterase, carbamate, pseudoirreversible inhibition Full text (file, 4,55 MB) This document has more files! More... |
8. Novel organoruthenium(II) complex C1 selectively inhibits butyrylcholinesterase without side effects on neuromuscular transmissionTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Iztok Turel, Robert Frangež, 2023, original scientific article Keywords: organoruthenium(II) complex, acetylcholinesterase, butyrylcholinesterase, mouse neuromuscular system, ruthenium, Alzheimer disease, neurodegenerative diseases Full text (file, 3,74 MB) This document has more files! More... |
9. 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseasesDamijan Knez, Anže Meden, Anja Pišlar, Janko Kos, Simon Žakelj, Jure Stojan, Stanislav Gobec, José Marco-Contelles, 2023, original scientific article Keywords: quinolylnitrone, butyrylcholinesterase, monoamine oxidase B, Alzheimer's disease, multifunctional ligands, 6-hydroxydopamine model, passive avoidance task, novel object recognition Full text (file, 3,96 MB) This document has more files! More... |