1. Določanje mehanizmov agregacije monoklonskih protiteles v bioloških zdravilihMitja Zidar, 2016, master's thesis Keywords: biofizika, proteini, monoklonska protitelesa, agregacija, koloidna stabilnost, konformacijska stabilnost, diferencialna kalorimetrija, gelska izključitvena kromatografija, dinamično sipanje svetlobe Full text (file, 3,47 MB) |
2. Fizikalna optimizacija procesov čiščenja bioloških zdravilMaša Lah, 2022, master's thesis Keywords: fizikalna optimizacija, agregacija, gelska izključitvena kromatografija, intrinzična proteinska fluorescenca, koloidna stabilnost, konformacijska stabilnost, monoklonska protitelesa, proteini Full text (file, 3,45 MB) |
3. Analysis and prediction of aggregation and degradation in protein-based biopharmaceuticalsMitja Zidar, 2020, doctoral dissertation Keywords: soft matter physics, monoclonal antibody, aggregation, degradation, viscosity, biopharmaceuticals, proteins Full text (file, 8,16 MB) |
4. Discovery of compounds with viscosity-reducing effects on biopharmaceutical formulations with monoclonal antibodiesMatic Proj, Mitja Zidar, Blaž Lebar, Nika Strašek Benedik, Goran Miličić, Aleš Žula, Stanislav Gobec, 2022, original scientific article Keywords: viscosity, protein formulations, biopharmaceuticals, viscosity-reducing agents, computational screening Full text (file, 2,19 MB) This document has more files! More... |
5. Polysorbate stabilityBlaž Lebar, Tinkara Lekić, Pija Košir, Miha Kastelic, Mitja Zidar, Janez Mravljak, Stane Pajk, 2024, original scientific article Keywords: polysorbates, primary packaging material, hydrolysis, stability, histidine, acetic acid, principal component analysis Full text (file, 2,69 MB) This document has more files! More... |
6. Alternative buffer systems in biopharmaceutical formulations and their effect on protein stabilityBlaž Lebar, Mitja Zidar, Janez Mravljak, Roman Šink, Aleš Žula, Stane Pajk, 2024, original scientific article Keywords: biopharmaceuticals, buffer, stress, aggregates, alternative buffers, stability Full text (file, 2,17 MB) This document has more files! More... |