20.500.12556/RUL-95486 Modeliranje sekundarne stopnje sušenja liofilizacijskega procesa Modeling the Secondary Drying Stage of Lyophilisation process V zaključnem delu smo obravnavali proces liofilizacije. Narava procesa nam omogoča odstranjevanje vode iz produktov, ne da je snov izpostavljena visokim temperaturam, ki lahko uničijo lastnosti produkta. To je en temeljnih procesov pri procesiranju farmacevtskih produktov in prehrane, ki ima velik vpliv na njihovo stabilnost in obstojnost hranjenja. Znotraj procesa smo se osredotočili na del procesa, ki se imenuje sekundarna stopnja sušenja. Sekundarno stopnjo sušenja okarakterizira odstranjevanje vode iz suhe snovi z desorpcijo. Predstavljene so teoretične osnove procesa, ki pomagajo razumeti delovanje procesa. Izdelali smo model sekundarne stopnje sušenja liofilizacijskega procesa, ki omogoča analizo vpliva ključnih parametrov na dinamiko procesa. Primerjava izračunanih z iz literature dobljenimi eksperimentalnimi vrednosti kaže obetavne rezultate. In this work we discussed the process of lyophilisation. The nature of process allows the removal of water from products, without them being exposed to higher temperatures that could potentially destroy their properties. It is one of the fundamental processes in the processing of pharmaceutical products and foods, and has an enormous impact on storage time and stability of said products. Within the process we focused on part of the process that is called secondary drying stage. Secondary drying stage is characterized by removal of water bound on the dried product with desorption. Theoretical principles of the process are presented to help us understand the process. A model of secondary drying stage of lyophilisation process is created, which enables the analysis of the influence of key parameters on dynamics of the process. The comparison of calculated values with the experimental values from literature has shown promising results. liofilizacija sekundarno sušenje prenos toplote in snovi matematični model desorpcija vode koeficient masnega prenosa lyophilisation secondary drying heat and mass transfer mathematical model water desorption coefficient of mass transfer true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2017-09-20 14:53:19 2017-09-20 14:53:19 2022-08-10 06:25:07 0000-00-00 00:00:00 2017 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1970-01-01 201381 1280.pdf 1280.pdf 1 37047BA7AD24F71C69945A5B4C77C162 0ece3cf4043d1ade2d34141121420d01e4a242dc20333d0cfbebafd7dcde7f4f c48a497d-a1b3-11eb-a523-00155dcfd717 20.500.12556/rul/8cf14f52-cbbb-46cc-9c32-b54972b3e203 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=104091 Fakulteta za strojništvo 0 0 0