20.500.12556/RUL-92922 Uporaba biotehnoloških metod za izboljšanje lastnosti medicinske konoplje (Cannabis sativa L.). Use of biotechnological methods for improving characteristics of medicinal cannabis (Cannabis sativa L.) Medicinska konoplja (Cannabis sativa L.) je rastlina, ki lahko zaradi vsebnosti kanabinoidov in drugih snovi, ki vplivajo na zdravje, marsikateremu bolniku izboljša življenje. Glavna kanabinoida, ki se nahajata v konoplji, sta delta-9-tetrahidrokanabinol (Δ9THC) in kanabidiol (CBD), ki se sintetizirata v žleznih trihomih. V človeku kanabinoidi delujejo preko endokanabinoidnega sistema. Δ9THC je psihoaktivna substanca, ki vpliva na povečanje apetita, zmanjšuje slabost, deluje proti bolečinam in stimulira imunski sistem, CBD pa poleg zdravilnih učinkov zmanjšuje neželene učinke Δ9THC. Zaradi vse večje uporabe konoplje v medicini je želja pridobiti rastline z različnimi vsebnostmi kanabinoidov in doseči čim večje donose za izolacijo. Uporaba biotehnoloških metod in razvoj novih protokolov za uspešno shranjevanje, razmnoževanje, gensko transformacijo in regeneracijo rastlin vodi v učinkovitejše žlahtnjenje medicinske konoplje. Medical cannabis (Cannabis sativa L.) is a plant which can improve the quality of life for many patients because the content of cannabinoids and other substances that affect health. The main cannabinoids in cannabis are delta-9-tetrahydrocannabinol (Δ9THC) and cannabidiol (CBD), which are synthesized in glandular trihomes. Cannabinoids work through the endocannabinoid system in humans. Δ9THC is a psychoactive substance that affects appetite, reduces nausea, acts against pain and stimulates the immune system. CBD, in addition to the therapeutic effects, reduces adverse effects of Δ9THC. Due to the increasing use of cannabis in medicine, the goal is to acquire plants with different cannabinoid contents and to achieve the highest possible yields in cannabinoids extractions. The use of biotechnological methods and the development of new protocols for successful storage, micropropagation, gene transformation, plant regeneration lead to more efficient breeding of medical cannabis. biotehnološke metode medicinska konoplja Cannabis sativa kanabinoidi žlahtnjenje rastlin biotechnological methods medicinal cannabis Cannabis sativa cannabinoids plant breeding true false false [R. Dorn] Slovenski jezik Angleški jezik Delo diplomskega seminarja/zaključno seminarsko delo/naloga 2017-07-09 07:15:12 2017-07-09 07:15:15 2022-08-10 01:20:19 0000-00-00 00:00:00 2017 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 633.522:602.6(043.2) 130886 8764793 709.pdf 709.pdf 1 D1BF243CBBB96C4CD13F747F3D79360B 8768315ded2ec5e39e841da32f5a9094f42b30ca2774c61528fa75e8736c7900 759771ca-a1b3-11eb-a523-00155dcfd717 20.500.12556/rul/dc4a465a-8ea6-4b4a-819d-9d4a3d1fdd53 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=101088 Biotehniška fakulteta 0 0 0